IKBIP Antibody

Volume : 50 µL
Clone Number :
Aliases : IKBIP antibody; IKIP antibody; Inhibitor of nuclear factor kappa-B kinase-interacting protein antibody; I kappa-B kinase-interacting protein antibody; IKBKB-interacting protein antibody; IKK-interacting protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q70UQ0
Immunogen : Fusion protein of Human IKBIP
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, IHC; ELISA : 1 : 2000-1 : 5000, IHC : 1 : 50-1 : 200
Background : IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic retic µLum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vasc µLar endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IKBIP
Research Areas : Cancer;Cell biology