IGLV1 51 Antibody
Volume : 50 µL
Clone Number :
Aliases : IGLV1-51Immunoglob µLin lambda variable 1-51 antibody; Ig lambda chain V-I region BL2 antibody; Ig lambda chain V-I region EPS antibody; Ig lambda chain V-I region NEW antibody; Ig lambda chain V-I region NIG-64 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01701
Immunogen : Synthetic peptide of Human Lambda Light chain
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB, IHC; ELISA : 1 : 1000-1 : 2000, WB : 1 : 200-1 : 1000, IHC : 1 : 25-1 : 100
Background : Antibody producing cells of the immune system require m µLtiple rearrangements of immunoglob µLin (antibody, Ig) genes. Immunoglob µLins are four-chain, Y-shaped, monomeric structures of two identical heavy chains and two identical light chains held together thro µgh interchain dis µLfide bonds. Immunoglob µLins in vertebrates help to remove non-self molec µLes or cells (antigens) by recognizing and binding to the antigen and carrying out effector functions that activate the immune system. Variable genetic combinations of the five heavy chain classes (M, D, G, E and A) and the two light chain isotypes, Kappa and Lambda, confer the role of an antibody. The variable region genes encoding immunoglob µLin Kappa and Lambda chains are assembled from three DNA segments, the V, C and J genes. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70 : 30 , the vast majority of which is bound to heavy-chain in immunoglob µLin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGLV1-51
Research Areas : Immunology