ITSN1 Antibody

Volume : 50 µg
Clone Number :
Aliases : Human intersectin SH3 domain containing protein SH3P17 antibody; Intersectin 1 SH3 domain protein antibody; intersectin 1 short form variant 3 antibody; intersectin 1 short form variant, 11 antibody; Intersectin short form antibody; intersectin short variant 12 antibody; Intersectin-1 antibody; Intersectin1 antibody; ITSN 1 antibody; ITSN antibody; itsn1 antibody; ITSN1_HUMAN antibody; MGC134948 antibody; MGC134949 antibody; OTTHUMP00000067855 antibody; OTTHUMP00000067856 antibody; OTTHUMP00000067857 antibody; OTTHUMP00000194810 antibody; OTTHUMP00000194811 antibody; OTTHUMP00000194812 antibody; OTTHUMP00000206688 antibody; SH3 domain containing protein 1A antibody; SH3 domain protein 1A antibody; SH3 domain-containing protein 1A antibody; SH3D1A antibody; SH3P17 antibody; Src homology 3 domain containing protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15811
Immunogen : Recombinant Human Intersectin-1 protein (773-916AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB, IHC; Recommended dilution : WB : 1 : 500-1 : 5000, IHC : 1 : 200-1 : 500
Background : Acts as guanine nucleotide exchange factor (GEF) specific for the CDC42 GTPase (By similarity). Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May reg µLate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 co µLd be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITSN1
Research Areas : Neuroscience; Signal transduction