IMPACT Antibody

Volume : 50 µg
Clone Number :
Aliases : IMPACT antibody; Impact homolog (mouse) antibody; Impact homolog antibody; impact RWD domain protein antibody; IMPCT_HUMAN antibody; Imprinted and ancient gene protein homolog antibody; MGC33718 antibody; Protein IMPACT antibody; RWD domain containing 5 antibody; RWDD5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2X3
Immunogen : Recombinant Human Protein IMPACT protein (41-320AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB, IHC; Recommended dilution : WB : 1 : 1000-1 : 5000, IHC : 1 : 20-1 : 200
Background : Translational reg µLator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1 thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-reg µLation of protein synthesis. May be required to reg µLate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Thro µgh its action on GCN2, may also facilitate neuritogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IMPACT
Research Areas : Epigenetics and Nuclear Signaling