INTU Antibody

Volume : 50 µg
Clone Number :
Aliases : Homolog of inturned (X. tropicalis) antibody; INT antibody; intu antibody; Inturned planar cell polarity effector homolog antibody; KIAA1284 antibody; PDZ domain containing 6 antibody; PDZ domain-containing protein 6 antibody; PDZD 6 antibody; PDZD6_HUMAN antibody; PDZK6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLD6
Immunogen : Recombinant Human Protein inturned protein (6-139AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC, IF; Recommended dilution : IHC : 1 : 200-1 : 500, IF : 1 : 50-1 : 200
Background : Plays a key role in ciliogenesis and embryonic development. Reg µLator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtub µLes. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed : 27158779).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : INTU
Research Areas : Cell biology; Stem cells