AMGO1 rabbit pAb - 100 μL

Function: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. similarity: Belongs to the immunoglobulin superfamily. AMIGO family. similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. similarity: Contains 6 LRR (leucine-rich) repeats. subcellular location: Associated with axons of neuronal cells. subunit: Binds itself as well as AMIGO2 and AMIGO3.