Rabies(Rab-50) , CF594 conjugate , 0.1mg / mL

Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This MAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded , neurotropic , negative sense RNA virus which encodes 5 proteins: a glycoprotein , a nucleoprotein , and three others. The mature virus has a bullet shape , a protein coat , and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus , with a very wide range of hosts. It causes an acute , central nervous system infection , characterized by CNS irritation , followed by paralysis and death. Approximately 50 , 000 human deaths each year are caused by rabies._x000D__x000D_Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.