Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P01730
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglob µLin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molec µLes) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 reg µLates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.1. Ledbetter, J et al. (1981) J Exp Med 153 : 310-323.2. Haynes , B et al. (1986) Leukocyte Typing II : Human T lymphocytes. New York : Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.
Clonality : Monoclonal
Isotype : IgG2b
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CD4
Research Areas : Immunology;Stem cells