Biotinilated

Volume : 50 µg
Clone Number :
Aliases : EXOSC3 antibody; RRP40 antibody; CGI-102Exosome complex component RRP40 antibody; Exosome component 3 antibody; Ribosomal RNA-processing protein 40 antibody; p10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT5
Immunogen : Recombinant Human Exosome complex component RRP40 protein (2-275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC9 and EXOSC5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Autoantigen PM/Scl 2 antibody; Exosc10 antibody; Exosome component 10 antibody; EXOSX_HUMAN antibody; P100 polymyositis scleroderma overlap syndrome associated autoantigen antibody; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen antibody; p2 antibody; p3 antibody; p4 antibody; PM Scl antibody; PM/Scl 100 antibody; PM/Scl-100 antibody; PMSCL antibody; PMSCL2 antibody; Polymyositis/scleroderma autoantigen 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 antibody; RRP6 antibody; Rrp6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01780
Immunogen : Recombinant Human Exosome component 10 protein (587-762AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3\'-5\' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC10
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : 3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y3B2
Immunogen : Recombinant Human Exosome complex component CSL4 protein (9-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC6 and EXOSC8.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : EXO84 antibody; Exo84p antibody; exoc8 antibody; EXOC8_HUMAN antibody; Exocyst complex 84 kDa subunit antibody; Exocyst complex component 8 antibody; SEC84 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IYI6
Immunogen : Recombinant Human Exocyst complex component 8 protein (508-725AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC8
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 2 5 3p antibody; DKFZp686J04253 antibody; EX070 antibody; EXO70 antibody; Exo70p antibody; EXOC 1 antibody; EXOC 7 antibody; EXOC1 antibody; Exoc7 antibody; EXOC7_HUMAN antibody; Exocyst complex component 7 antibody; Exocyst complex component Exo70 antibody; FLJ40965 antibody; FLJ46415 antibody; KIAA1067 antibody; Rexo70 antibody; YJL085W antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UPT5
Immunogen : Recombinant Human Exocyst complex component 7 protein (521-735AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to ins µLin, perhaps directing the vesicle to the precise site of fusion (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC7
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : EXOC 3 antibody; Exoc3 antibody; EXOC3_HUMAN antibody; Exocyst complex component 3 antibody; Exocyst complex component Sec 6 antibody; Exocyst complex component Sec6 antibody; rSec 6 antibody; Sec 6 antibody; Sec 6 homolog antibody; Sec 6p antibody; Sec6 antibody; SEC6 L1 antibody; SEC6 like 1 antibody; Sec6 protein antibody; SEC6L1 antibody; Sec6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60645
Immunogen : Recombinant Human Exocyst complex component 3 protein (410-756AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC3
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : exo1 antibody; EXO1_HUMAN antibody; ExoI antibody; Exonuclease 1 antibody; Exonuclease I antibody; Exonuclease1 antibody; HEX1 antibody; hExo I antibody; hExo1 antibody; hExoI antibody; Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ84
Immunogen : Recombinant Human Exonuclease 1 protein (301-600AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : 5\'->3\' double-stranded DNA exonuclease which may also possess a cryptic 3\'->5\' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5\' or 3\' to the mismatch. Also exhibits endonuclease activity against 5\'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglob µLin genes. Essential for male and female meiosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXO1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : 4930539P14Rik antibody; C14orf114 antibody; C85658 antibody; DKFZp781A0133 antibody; DKFZp781L15100 antibody; Exd2 antibody; EXD2_HUMAN antibody; EXDL2 antibody; Exonuclease 3''-5'' domain-containing protein 2 antibody; Exonuclease 3''-5'' domain-like-containing protein 2 antibody; exonuclease 3'-5' domain-like 2 antibody; FLJ10738 antibody; RGD1311087 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NVH0
Immunogen : Recombinant Human Exonuclease 3\\\'-5\\\' domain-containing protein 2 protein (137-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection thro µgh its 3\\\'-5\\\' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXD2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : EVI2A antibody; EVDA antibody; EVI2Protein EVI2A antibody; Ecotropic viral integration site 2A protein homolog antibody; EVI-2A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22794
Immunogen : Recombinant Human Protein EVI2A protein (31-133AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EVI2A
Research Areas : Cancer

Volume : 50 µg
Clone Number :
Aliases : EVC2 antibody; LBN antibody; Limbin antibody; Ellis-van Creveld syndrome protein 2 antibody; EVC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86UK5
Immunogen : Recombinant Human Limbin protein (30-199AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Positive reg µLator of the hedgehog signaling pathway (By similarity). Plays a critical role in bone formation and skeletal development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EVC2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : EVCEllis-van Creveld syndrome protein antibody; DWF-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P57679
Immunogen : Recombinant Human Ellis-van Creveld syndrome protein (493-602AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as a positive mediator of Hedgehog signaling indispensable for normal endochondral growth and skeletal development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EVC
Research Areas : Developmental biology