Volume : 50 µg
Clone Number :
Aliases : E2F 4 antibody; E2F transcription factor 4 antibody; E2F transcription factor 4 p107/p130 binding antibody; E2F-4 antibody; E2F4 antibody; E2F4_HUMAN antibody; p107/p130 binding protein antibody; Transcription factor E2F 4 antibody; Transcription factor E2F4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16254
Immunogen : Recombinant Human Transcription factor E2F4 protein (160-299AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription activator that binds DNA cooperatively with DP proteins thro µgh the E2 recognition site, 5\'-TTTC[CG]CGC-3\' found in the promoter region of a number of genes whose products are involved in cell cycle reg µLation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for m µLticiliate cell differentiation : together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : E2F4
Research Areas : Epigenetics and Nuclear Signaling; Stem cells