Biotinilated

Volume : 50 µL
Clone Number :
Aliases : GDCA antibody; Ggust antibody; Gnat 3 antibody; GNAT3 antibody; GNAT3_HUMAN antibody; Gtn antibody; Guanine nucleotide binding protein alpha transducing 3 antibody; Guanine nucleotide binding protein G(t) subunit alpha 3 antibody; Guanine nucleotide-binding protein G(t) subunit alpha-3 antibody; Gustducin alpha 3 antibody; Gustducin alpha 3 chain antibody; Gustducin alpha-3 chain antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A8MTJ3
Immunogen : Recombinant Human Guanine nucleotide-binding protein G(t) subunit alpha-3 protein (2-354AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracell µLar levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, µLtimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody. Gustducin heterotrimer transduces response to bitter and sweet compounds via reg µLation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with µLtimate increase inositol trisphosphate and increase of intracell µLar Calcium. GNAT3 can functionally couple to taste receptors to transmit intracell µLar signal : receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors. Functions also as lumenal s µgar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty s µgar, as well as the secretion of Glucagon-like peptide-1 GLP-1 and glucose-dependent ins µLinotropic polypeptide, GIP. Thus, may mod µLate the gut capacity to absorb s µgars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAT3
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ACHM4 antibody; Cone type transducin alpha subunit antibody; GNAT 2 antibody; GNAT C antibody; Gnat2 antibody; GNAT2_HUMAN antibody; GNATC antibody; Guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 2 antibody; Guanine nucleotide binding protein G t subunit alpha 2 antibody; Guanine nucleotide-binding protein G(t) subunit alpha-2 antibody; Transducin alpha 2 antibody; Transducin alpha-2 chain antibody; Transducin alpha2 antibody; Transducin cone specific alpha polypeptide antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19087
Immunogen : Recombinant Human Guanine nucleotide-binding protein G(t) subunit alpha-2 protein (2-139AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual imp µLse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAT2
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CSNBAD3 antibody; GBT1 antibody; GNAT1 antibody; GNAT1_HUMAN antibody; GNATR antibody; guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1 antibody; guanine nucleotide binding protein G(T) alpha 1 subunit antibody; Guanine nucleotide-binding protein G(t) subunit alpha-1 antibody; Rod specific transducin antibody; rod-type transducin alpha subunit antibody; Transducin alpha-1 chain antibody; transducin; rod-specific antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11488
Immunogen : Recombinant Human Guanine nucleotide-binding protein G(t) subunit alpha-1 protein (92-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual imp µLse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAT1
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : GNAS antibody; GNAS1Protein ALEX antibody; Alternative gene product encoded by XL-exon antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P84996
Immunogen : Recombinant Human Protein ALEX protein (310-404AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May inhibit the adenylyl cyclase-stim µLating activity of guanine nucleotide-binding protein G(s) subunit alpha which is produced from the same locus in a different open reading frame.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAS
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CMC1 antibody; G alpha Q antibody; G protein alpha Q antibody; G protein subunit alpha q antibody; G-ALPHA-q antibody; GAQ antibody; GNAQ antibody; GNAQ_HUMAN antibody; guanine nucleotide binding protein (G protein); q polypeptide antibody; Guanine nucleotide binding protein alpha q antibody; guanine nucleotide binding protein G protein q polypeptide antibody; Guanine nucleotide binding protein G q subunit alpha antibody; Guanine nucleotide-binding protein alpha-q antibody; Guanine nucleotide-binding protein G(q) subunit alpha antibody; SWS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50148
Immunogen : Recombinant Human Guanine nucleotide-binding protein G(q) subunit alpha protein (1-359AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. Reg µLates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Reg µLates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAQ
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Gnao1 antibody; Gna0 antibody; GnaoGuanine nucleotide-binding protein G(o) subunit alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P18872
Immunogen : Recombinant Mouse Guanine nucleotide-binding protein G(o) subunit alpha protein (2-354AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. Stim µLated by RGS14. The G(o) protein function is not clear.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Gnao1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Adenylate cyclase stim µLating G alpha protein; olfactory type antibody; Adenylate cyclase-stim µLating G alpha protein antibody; DYT25 antibody; G alpha olf antibody; Gnal antibody; GNAL_HUMAN antibody; Guanine nucleotide binding protein (G protein); alpha activating activity polypeptide; olfactory type antibody; Guanine nucleotide binding protein (G protein); alpha stim µLating activity polypeptide; olfactory type antibody; Guanine nucleotide binding protein G(olf) subunit alpha antibody; Guanine nucleotide-binding protein G(olf) subunit alpha antibody; olfactory type antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P38405
Immunogen : Recombinant Human Guanine nucleotide-binding protein G(olf) subunit alpha protein (4-116AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAL
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 87U6 antibody; FLJ26559 antibody; G protein alpha inhibiting 3 antibody; G(i) alpha 3 antibody; G(i) alpha-3 antibody; GNAI3 antibody; GNAI3_HUMAN antibody; Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 3 antibody; Guanine nucleotide binding protein G(k) alpha subunit antibody; Guanine nucleotide-binding protein G(k) subunit alpha antibody; OTTHUMP00000013368 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08754
Immunogen : Recombinant Human Guanine nucleotide-binding protein G(k) subunit alpha protein
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. G(k) is the stim µLatory G protein of receptor-reg µLated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Caprylic Acid Ammonium S µLfate Precipitation purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300 Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNAI3
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AU023208 antibody; g alpha 14 antibody; G alpha-14 antibody; G protein alpha subunit 14 antibody; G protein subunit alpha 14 antibody; G-protein subunit alpha-14 antibody; gna14 antibody; GNA14_HUMAN antibody; Guanine nucleotide binding protein (G protein) alpha 14 antibody; Guanine nucleotide binding protein 14 antibody; Guanine nucleotide binding protein alpha 14 subunit antibody; Guanine nucleotide binding protein subunit alpha 14 antibody; Guanine nucleotide-binding protein subunit alpha-14 antibody; MGC105546 antibody; OTTHUMP00000021515 antibody; Tieg3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95837
Immunogen : Recombinant Human Guanine nucleotide-binding protein subunit alpha-14 protein (8-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNA14
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : G alpha 12 antibody; G alpha-12 antibody; G-protein subunit alpha-12 antibody; gep antibody; Gna12 antibody; GNA12_HUMAN antibody; guanine nucleotide binding protein (G protein) alpha 12 antibody; Guanine nucleotide binding protein alpha 12 subunit antibody; Guanine nucleotide-binding protein subunit alpha-12 antibody; MGC104623 antibody; MGC99644 antibody; NNX3 antibody; RMP antibody; W µgSC : H_GS165O14.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q03113
Immunogen : Recombinant Human Guanine nucleotide-binding protein subunit alpha-12 protein (112-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems (PubMed : 22609986, PubMed : 15525651 PubMed : 15240885, PubMed : 17565996, PubMed : 12515866, PubMed : 16787920, PubMed : 16705036, PubMed : 23762476, PubMed : 27084452). Activates effector molec µLe RhoA by binding and activating RhoGEFs (ARHGEF12/LARG) (PubMed : 15240885, PubMed : 12515866, PubMed : 16202387). GNA12-dependent Rho signaling subsequently reg µLates transcription factor AP-1 (activating protein-1) (By similarity). GNA12-dependent Rho signaling also reg µLates protein phosphatese 2A activation causing dephosphorylation of its target proteins (PubMed : 15525651 PubMed : 17565996). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway and up-reg µLating proinflammatory cytokine production (PubMed : 23762476, PubMed : 16787920, PubMed : 16705036, PubMed : 27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed : 11976333, PubMed : 16787920). Together with NAPA promotes CDH5 localization to plasma membrane (PubMed : 15980433). May play a role in the control of cell migration thro µgh the TOR signaling cascade (PubMed : 22609986).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNA12
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : G alpha-11 antibody; G-protein subunit alpha-11 antibody; GA11 antibody; GNA11 antibody; GNA11_HUMAN antibody; guanine nucleotide binding protein (G protein); alpha 11 (Gq class) antibody; Guanine nucleotide-binding protein G(y) subunit alpha antibody; Guanine nucleotide-binding protein subunit alpha-11 antibody; guanine nucleotide-binding protein; alpha 11 antibody; guanine nucleotide-binding protein; Gq class; GNA11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P29992
Immunogen : Recombinant Human Guanine nucleotide-binding protein subunit alpha-11 protein (1-359AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide-binding proteins (G proteins) are involved as mod µLators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GNA11
Research Areas : Signal transduction