Volume : 50 µg
Clone Number :
Aliases : ARF GAP GIT1 antibody; ARF GTPase activating protein GIT1 antibody; ARF GTPase-activating protein GIT1 antibody; CAT 1 antibody; CAT-1 antibody; CaT1 antibody; Cool associated and tyrosine phosphorylated protein 1 antibody; Cool-associated and tyrosine-phosphorylated protein 1 antibody; G protein coupled receptor kinase interacting ArfGAP 1 antibody; G protein coupled receptor kinase interactor 1 antibody; G protein-coupled receptor kinase-interactor 1 antibody; GIT1 antibody; GIT1_HUMAN antibody; GRK interacting protein 1 antibody; GRK-interacting protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2X7
Immunogen : Recombinant Human ARF GTPase-activating protein GIT1 protein (470-642AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molec µLes to form signaling mod µLes controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the Volume and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the reg µLation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GIT1
Research Areas : Signal transduction