Volume : 50 µg
Clone Number :
Aliases : 12,3-ketoacyl-CoA reductase,short chain antibody; 17 beta HSD 12 antibody; 17 beta hydroxysteroid dehydrogenase 12 antibody; 17-@beta-HSD XII antibody; 17-@beta-hydroxysteroid dehydrogenase XII antibody; 17-beta-HSD 12 antibody; 17-beta-hydroxysteroid dehydrogenase 12 antibody; 17beta HSD type 12 antibody; 3 ketoacyl CoA reductase antibody; 3-ketoacyl-CoA reductase antibody; DHB12_HUMAN antibody; Estradiol 17 beta dehydrogenase 12 antibody; Estradiol 17-beta-dehydrogenase 12 antibody; HSD17B12 antibody; Hydroxysteroid (17-beta) dehydrogenase 12 antibody; KAR antibody; KIK-I antibody; Kik1 antibody; SDR12C1 antibody; Short chain dehydrogenase/reductase family 12C member 1 antibody; Steroid dehydrogenase homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q53GQ0
Immunogen : Recombinant Human Very-long-chain 3-oxoacyl-CoA reductase protein (40-181AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic retic µLum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate to the production of VLCFAs of different chain lengths that are involved in m µLtiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HSD17B12
Research Areas : Cell biology; Metabolism; Signal transduction