Volume : 50 µg
Clone Number :
Aliases : FLJ20300 antibody; BAAT antibody; BAAT_HUMAN antibody; BACAT antibody; BAT antibody; Bile acid CoA : amino acid N-acyltransferase (glycine N-choloyltransferase) antibody; Bile acid CoA : amino acid N acyltransferase antibody; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody; Bile acid Coenzyme A : amino acid N acyltransferase antibody; Bile acid-CoA : amino acid N-acyltransferase antibody; Glycine N choloyltransferase antibody; Glycine N-choloyltransferase antibody; Long chain fatty acyl CoA hydrolase antibody; Long-chain fatty-acyl-CoA hydrolase antibody; MGC104432 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14032
Immunogen : Recombinant Human Bile acid-CoA : amino acid N-acyltransferase protein (313-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conj µgation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canalic µLi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic retic µLum (secondary bile acids). May catalyze the conj µgation of primary or secondary bile acids, or both. The conj µgation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconj µgated by bacteria in the intestine and are recycled back to the liver for reconj µgation (secondary bile acids). May also act as an acyl-CoA thioesterase that reg µLates intracell µLar levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conj µgates glycine to these acyl-CoAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BAAT
Research Areas : Cancer; Metabolism; Signal transduction