FITC

Volume : 50 µg
Clone Number :
Aliases : C12orf65 antibody; My030Probable peptide chain release factor C12orf65 antibody; mitochondrial antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H3J6
Immunogen : Recombinant Human Probable peptide chain release factor C12orf65, mitochondrial protein (36-166AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May act as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion. May help rescuing stalled mitoribosomes during translation (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C12orf65
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : C12orf60Uncharacterized protein C12orf60 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5U649
Immunogen : Recombinant Human Uncharacterized protein C12orf60 protein (1-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C12orf60
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : C10_HUMAN antibody; C12orf57 antibody; Protein C10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99622
Immunogen : Recombinant Human Protein C10 protein (2-126AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In brain, may be required for corpus callusum development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C12orf57
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CH3L2_HUMAN antibody; CHI3L2 antibody; Chitinase 3 like 2 antibody; Chitinase-3-like protein 2 antibody; Chondrocyte protein 39 antibody; OTTHUMP00000014028 antibody; YKL 39 antibody; YKL-39 antibody; YKL39 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15782
Immunogen : Recombinant Human Chitinase-3-like protein 2 protein (27-390AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHI3L2
Research Areas : Stem cells

Volume : 50 µg
Clone Number :
Aliases : CCB peptide antibody; Cg B antibody; CgB antibody; Chgb antibody; Chromogranin-B antibody; ChromograninB antibody; SCG1 antibody; SCG1_HUMAN antibody; Secretogranin 1 antibody; Secretogranin B antibody; Secretogranin I antibody; SgI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05060
Immunogen : Recombinant Human Secretogranin-1 protein (328-677AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Secretogranin-1 is a neuroendocrine secretory gran µLe protein, which may be the precursor for other biologically active peptides.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGB
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : beta Granin antibody; betagranin (N-terminal fragment of chromogranin A) antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; Pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10645
Immunogen : Recombinant Human Chromogranin-A protein (19-457AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Pancreastatin strongly inhibits glucose induced ins µLin release from the pancreas.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGA
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Checkpoint with forkhead and ring finger domains antibody; Checkpoint with forkhead and RING finger domains protein antibody; Chfr antibody; CHFR_HUMAN antibody; E3 ubiquitin protein ligase CHFR antibody; E3 ubiquitin-protein ligase CHFR antibody; EC 6.3.2. antibody; FLJ10796 antibody; FLJ33629 antibody; RING finger protein 196 antibody; RNF 116 antibody; RNF 196 antibody; RNF116 antibody; RNF196 antibody; Ubiquitin ligase protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EP1
Immunogen : Recombinant Human E3 ubiquitin-protein ligase CHFR protein (141-422AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtub µLe poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtub µLe poisons by mediating the \\\'Lys-48\\\'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1 leading to its degradation. May also promote the formation of \\\'Lys-63\\\'-linked polyubiquitin chains and functions with the specific ubiquitin-conj µgating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at \\\'Lys-63\\\' are usually not targeted for degradation, but are rather involved in signaling cell µLar stress.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHFR
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk2 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Reg µLates cell cycle checkpoint arrest thro µgh phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Reg µLates DNA repair thro µgh phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stim µLates the transcription of genes involved in DNA repair (including BRCA2) thro µgh the phosphorylation and activation of the transcription factor FOXM1. Reg µLates apoptosis thro µgh the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at \\\'Ser-20\\\' by CHEK2 may alleviate inhibition by MDM2, leading to accum µLation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes thro µgh phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells. Promotes the CCAR2-SIRT1 association and is required for CCAR2-mediated SIRT1 inhibition (PubMed : 25361978).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : C85740 antibody; Cell cycle checkpoint kinase antibody; Checkpoint ; S. pombe; homolog of; 1 antibody; Checkpoint kinase 1 antibody; Checkpoint kinase 1 homolog (S. pombe) antibody; CHEK 1 antibody; Chek1 antibody; Chk 1 antibody; Chk1 antibody; CHK1 checkpoint homolog (S. pombe) antibody; CHK1_HUMAN antibody; EC 2.7.11.1 antibody; rad27 antibody; Serine/threonine protein kinase Chk1 antibody; Serine/threonine-protein kinase CHK1 antibody; STT3; subunit of the oligosaccharyltransferase complex; homolog A (S. cerevisiae) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14757
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk1 protein (258-370AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. This reg µLation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at \'Ser-178\' and \'Thr-507\' and phosphorylation of CDC25C at \'Ser-216\' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at \'Ser-76\', \'Ser-124\', \'Ser-178\', \'Ser-279\' and \'Ser-293\' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at \'Ser-76\' primes the protein for subsequent phosphorylation at \'Ser-79\', \'Ser-82\' and \'Ser-88\' by NEK11 which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at \'Thr-309\', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates m µLtiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cell µLar proliferation. Also promotes repair of DNA cross-links thro µgh phosphorylation of FANCE. Binds to and phosphorylates TLK1 at \'Ser-743\', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance thro µgh reg µLation of PCNA. May reg µLate the transcription of genes that reg µLate cell-cycle progression thro µgh the phosphorylation of histones. Phosphorylates histone H3.1 (to form H3T11ph), which leads to epigenetic inhibition of a subset of genes. May also phosphorylate RB1 to promote its interaction with the E2F family of transcription factors and subsequent cell cycle arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK1
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : CDH antibody; CHD antibody; CHDH antibody; CHDH_HUMAN antibody; Choline dehydrogenase antibody; mitochondrial antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NE62
Immunogen : Recombinant Human Choline dehydrogenase, mitochondrial protein (30-223AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : mitochondrial inner membrane, choline dehydrogenase activity, choline catabolic process
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHDH
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ATP-dependent helicase CHD5 antibody; CHD 5 antibody; CHD-5 antibody; CHD5 antibody; CHD5_HUMAN antibody; Chromodomain-helicase-DNA-binding protein 5 antibody; DKFZp434N231 antibody; KIAA0444 antibody; RP1-233K16.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TDI0
Immunogen : Recombinant Human Chromodomain-helicase-DNA-binding protein 5 protein (1600-1699AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Chromatin-remodeling protein that binds DNA thro µgh histones and reg µLates gene transcription. May specifically recognize and bind trimethylated \'Lys-27\' (H3K27me3) and non-methylated \'Lys-4\' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively reg µLate the trimethylation of histone H3 at \'Lys-27\' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it reg µLates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively reg µLates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably reg µLates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHD5
Research Areas : Epigenetics and Nuclear Signaling