FITC

Volume : 50 µg
Clone Number :
Aliases : Docking protein 2 56kDa antibody; Docking protein 2 antibody; DOK 2 antibody; DOK R antibody; DOK2 antibody; DOK2_HUMAN antibody; Downstream of tyrosine kinase 2 antibody; OTTHUMP00000161710 antibody; OTTHUMP00000224923 antibody; p56(dok 2) antibody; p56(dok-2) antibody; p56dok 2 antibody; p56DOK antibody; p56dok2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60496
Immunogen : Recombinant Human Docking protein 2 protein (123-412AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of m µLtimolec µLar signaling complexes. DOK2 may mod µLate the cell µLar proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in mod µLating Bcr-Abl signaling. Attenuates EGF-stim µLated MAP kinase activation (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOK2
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Docking protein 1 62kD antibody; Docking protein 1 antibody; DOK 1 antibody; DOK1 antibody; DOK1_HUMAN antibody; Downstream of tyrosine kinase 1 antibody; p62(dok) antibody; P62DOK antibody; pp62 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99704
Immunogen : Recombinant Human Docking protein 1 protein (1-481AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of m µLtimolec µLar signaling complexes. DOK1 appears to be a negative reg µLator of the ins µLin signaling pathway. Mod µLates integrin activation by competing with talin for the same binding site on ITGB3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOK1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Deoxyhypusine dioxygenase antibody; Deoxyhypusine hydroxylase antibody; Deoxyhypusine hydroxylase/monooxygenase antibody; Deoxyhypusine monooxygenase antibody; Dohh antibody; DOHH_HUMAN antibody; hDOHH antibody; HEAT like (PBS lyase) repeat containing 1 antibody; HEAT like PBS lyase repeat containing antibody; HEAT like repeat containing protein 1 antibody; HEAT-like repeat-containing protein 1 antibody; HLRC1 antibody; MGC4293 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BU89
Immunogen : Recombinant Human Deoxyhypusine hydroxylase protein (79-159AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOHH
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DODA4,5-DOPA dioxygenase extradiol antibody; EC 1.13.11.29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Port µLaca grandiflora (Rose moss)
UniProt ID : Q7XA48
Immunogen : Recombinant Port µLaca grandiflora 4,5-DOPA dioxygenase extradiol protein (1-271AA)
Raised in : Rabbit
Species Reactivity : Port µLaca grandiflora
Tested Applications :
Background : Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DODA
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DOCK7 antibody; KIAA1771Dedicator of cytokinesis protein 7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96N67
Immunogen : Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed : 16982419). Has a role in pigmentation (By similarity). Involved in the reg µLation of cortical neurogenesis thro µgh the control of radial glial cells (RGCs) proliferation versus differentiation; negatively reg µLates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtub µLe growth-promoting function of TACC3 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK7
Research Areas : Neuroscience; Developmental biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dedicator of cytokinesis protein 6 antibody; Dock6 antibody; DOCK6_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96HP0
Immunogen : Recombinant Human Dedicator of cytokinesis protein 6 protein (499-616AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Thro µgh its activation of CDC42 and RAC1 may reg µLate neurite outgrowth (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK6
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DOCK5Dedicator of cytokinesis protein 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H7D0
Immunogen : Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK5
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DOCK3 antibody; KIAA0299 antibody; MOCADedicator of cytokinesis protein 3 antibody; Modifier of cell adhesion antibody; Presenilin-binding protein antibody; PBP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IZD9
Immunogen : Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stim µLate Tau/MAPT phosphorylation s µggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, s µggesting that it may affect the function of some small GTPase involved in the reg µLation of actin cytoskeleton or cell adhesion receptors (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK3
Research Areas : Neuroscience; Stem cells

Volume : 50 µg
Clone Number :
Aliases : DOCK10 antibody; KIAA0694 antibody; ZIZ3Dedicator of cytokinesis protein 10 antibody; Zizimin-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96BY6
Immunogen : Recombinant Human Dedicator of cytokinesis protein 10 protein (1645-2186AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK10
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 180 kDa protein downstream of CRK antibody; Ced5 antibody; Dedicator of Cytokinesis 1 antibody; Dedicator of cytokinesis protein 1 antibody; DOCK 1 antibody; DOCK 180 antibody; DOCK1 antibody; DOCK1_HUMAN antibody; DOCK180 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14185
Immunogen : Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1 mediates CRK/CRKL reg µLation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed : 19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed : 8657152).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK1
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Doc2 beta antibody; Doc2-beta antibody; Doc2b antibody; DOC2B_HUMAN antibody; DOC2BL antibody; Double C2 like domain containing protein beta antibody; Double C2 like domains beta antibody; Double C2 like domains beta like antibody; Double C2-like domain-containing protein beta antibody; OTTMUSP00000006522 antibody; RP23 78H4.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14184
Immunogen : Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Calcium sensor which positively reg µLates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stim µLate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stim µLated ins µLin secretion in pancreatic cells and ins µLin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOC2B
Research Areas : Neuroscience; Signal transduction