FITC

Volume : 50 µg
Clone Number :
Aliases : EH domain containing 2 antibody; EH domain containing 3 antibody; EH domain containing protein 2 antibody; EH domain-containing protein 2 antibody; EHD 2 antibody; Ehd2 antibody; EHD2_HUMAN antibody; EHD3 antibody; FLJ96617 antibody; PAST 2 antibody; PAST homolog 2 antibody; PAST2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZN4
Immunogen : Recombinant Human EH domain-containing protein 2 protein (401-543AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : ATP- and membrane-binding protein that controls membrane reorganization/tub µLation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes (PubMed : 17233914). Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EHD2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CDABP0131 antibody; EH domain containing 1 antibody; EH domain-containing protein 1 antibody; EHD1 antibody; EHD1_HUMAN antibody; FLJ42622 antibody; FLJ44618 antibody; H PAST antibody; hPAST1 antibody; PAST antibody; PAST homolog 1 antibody; PAST1 antibody; Testilin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H4M9
Immunogen : Recombinant Human EH domain-containing protein 1 protein (401-498AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : ATP- and membrane-binding protein that controls membrane reorganization/tub µLation upon ATP hydrolysis. In vitro causes vesic µLation of endocytic membranes (PubMed : 24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed : 15020713, PubMed : 17233914, PubMed : 20801876). Recruited to endosomal membranes upon nerve growth factor stim µLation, indirectly reg µLates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis (PubMed : 25686250).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EHD1
Research Areas : Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EHBP1 antibody; KIAA0903 antibody; NACSINEH domain-binding protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NDI1
Immunogen : Recombinant Human EH domain-binding protein 1 protein (1-106AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EHBP1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : egsA antibody; araMGlycerol-1-phosphate dehydrogenase [NAD(P)+] antibody; G1P dehydrogenase antibody; G1PDH antibody; EC 1.1.1.261 antibody; Enantiomeric glycerophosphate synthase antibody; sn-glycerol-1-phosphate dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Geobacillus stearothermophilus (Bacillus stearothermophilus)
UniProt ID : B3EYN8
Immunogen : Recombinant Geobacillus stearothermophilus Glycerol-1-phosphate dehydrogenase [NAD(P)+] protein (1-404AA)
Raised in : Rabbit
Species Reactivity : Geobacillus stearothermophilus
Tested Applications :
Background : Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : egsA
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : EGR3 antibody; PILOTEarly growth response protein 3 antibody; EGR-3 antibody; Zinc finger protein pilot antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06889
Immunogen : Recombinant Human Early growth response protein 3 protein (201-281AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable transcription factor involved in muscle spindle development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EGR3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AT591 antibody; CMT1D antibody; CMT4E antibody; DKFZp686J1957 antibody; E3 SUMO-protein ligase EGR2 antibody; Early growth response 2 antibody; Early growth response protein 2 antibody; EGR-2 antibody; egr2 antibody; EGR2_HUMAN antibody; FLJ14547 antibody; KROX 20 Drosophila homolog antibody; Krox 20 homolog Drosophila antibody; KROX-20; Drosophila; homolog (early growth response-2) antibody; KROX20 antibody; Krox20 protein antibody; Zinc finger protein Krox-20 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11161
Immunogen : Recombinant Human E3 SUMO-protein ligase EGR2 protein (42-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EGR2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 50 µg
Clone Number :
Aliases : AT225 antibody; Early growth response 1 antibody; Early growth response protein 1 antibody; EGR 1 antibody; EGR-1 antibody; EGR1 antibody; EGR1_HUMAN antibody; G0S30 antibody; KROX 24 antibody; KROX24 antibody; Nerve growth factor-induced clone A antibody; Nerve growth factor-induced protein A antibody; NGFI-A antibody; NGFIA antibody; TIS8 antibody; Transcription factor ETR103 antibody; Transcription factor Zif268 antibody; ZIF 268 antibody; ZIF268 antibody; Zinc finger protein 225 antibody; Zinc finger protein Krox-24 antibody; ZNF225 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18146
Immunogen : Recombinant Human Early growth response protein 1 protein (444-543AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptional reg µLator. Recognizes and binds to the DNA sequence 5\'-CGCCCCCGC-3\'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EGR1
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : Egln3Egl nine homolog 3 antibody; EC 1.14.11.29 antibody; Hypoxia-inducible factor prolyl hydroxylase 3 antibody; HIF-PH3 antibody; HIF-prolyl hydroxylase 3 antibody; HPH-3 antibody; Prolyl hydroxylase domain-containing protein 3 antibody; PHD3 antibody; SM-20 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : Q91UZ4
Immunogen : Recombinant Mouse Egl nine homolog 3 protein (2-239AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Cell µLar oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylation on the NODD site by EGLN3 appears to require prior hydroxylation on the CODD site. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation res µLting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. ELGN3 is the most important isozyme in limiting physiological activation of HIFs (partic µLarly HIF2A) in hypoxia. Also hydroxylates PKM in hypoxia, limiting glycolysis. Under normoxia, hydroxylates and reg µLates the stability of ADRB2. Reg µLator of cardiomyocyte and neuronal apoptosis. In cardiomyocytes, inhibits the anti-apoptotic effect of BCL2 by disrupting the BAX-BCL2 complex. In neurons, has a NGF-induced proapoptotic effect, probably thro µgh reg µLating CASP3 activity. Also essential for hypoxic reg µLation of neutrophilic inflammation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Egln3
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cardiovasc µLar; Metabolism

Volume : 50 µg
Clone Number :
Aliases : DKFZp434E026 antibody; EGL nine (C.elegans) homolog 2 antibody; Egl nine homolog 2 (C. elegans) antibody; Egl nine homolog 2 antibody; EGLN 2 antibody; EGLN2 antibody; EGLN2_HUMAN antibody; EIT 6 antibody; EIT6 antibody; Estrogen-induced tag 6 antibody; HIF P4H 1 antibody; HIF PH1 antibody; HIF prolyl hydroxylase 1 antibody; HIF-PH1 antibody; HIF-prolyl hydroxylase 1 antibody; HIFPH 1 antibody; HIFPH1 antibody; HPH 3 antibody; HPH-1 antibody; HPH-3 antibody; HPH3 antibody; Hypoxia inducible factor prolyl hydroxylase 1 antibody; Hypoxia-inducible factor prolyl hydroxylase 1 antibody; P4H1 antibody; PHD 1 antibody; PhD1 antibody; prolyl hydroxylase domain containing protein 1 antibody; Prolyl hydroxylase domain-containing protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96KS0
Immunogen : Recombinant Human Egl nine homolog 2 protein (283-407AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cell µLar oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation res µLting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN2 is involved in reg µLating hypoxia tolerance and apoptosis in cardiac and skeletal muscle. Also reg µLates susceptibility to normoxic oxidative neuronal death. Links oxygen sensing to cell cycle and primary cilia formation by hydroxylating the critical centrosome component CEP192 which promotes its ubiquitination and subsequent proteasomal degradation. Hydroxylates IKBKB, mediating NF-kappaB activation in hypoxic conditions. Target proteins are preferencially recognized via a LXXLAP motif.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EGLN2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cardiovasc µLar; Metabolism

Volume : 50 µg
Clone Number :
Aliases :
Product Type : polyclonal Ab Antibody
Immunogen Species : Zebrafish
UniProt ID : F1RA48
Immunogen : Recombinant Zebrafish Epidermal growth factor receptor protein (21-389AA)
Raised in : Rabbit
Species Reactivity : Zebrafish
Tested Applications :
Background : blood vessel lumenization
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : egfra
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody; Cell growth inhibiting protein 40 antibody; Cell proliferation inducing protein 61 antibody; EGF R antibody; EGFR antibody; EGFR_HUMAN antibody; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody; Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) antibody; Epidermal growth factor receptor antibody; erb-b2 receptor tyrosine kinase 1 antibody; ERBB antibody; ERBB1 antibody; Errp antibody; HER1 antibody; mENA antibody; NISBD2 antibody; Oncogen ERBB antibody; PIG61 antibody; Proto-oncogene c-ErbB-1 antibody; Receptor tyrosine protein kinase ErbB 1 antibody; Receptor tyrosine-protein kinase ErbB-1 antibody; SA7 antibody; Species antigen 7 antibody; Urogastrone antibody; v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody; wa2 antibody; Wa5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P00533
Immunogen : Recombinant Human Epidermal growth factor receptor protein (1067-1210AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracell µLar cues into appropriate cell µLar responses. Known ligands include EGF, TGFA/TGF-alpha, amphireg µLin, epigen/EPGN, BTC/betacell µLin, epireg µLin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs mod µLes. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EGFR
Research Areas : Cancer; Signal transduction