FITC

Volume : 50 µg
Clone Number :
Aliases : CD antibody; CELIAC1 antibody; DC 1 alpha chain antibody; DC alpha antibody; DC-1 alpha chain antibody; DC-alpha antibody; DC1; included antibody; DQ alpha 1 chain antibody; DQ-A1 antibody; DQ-DRW9 alpha chain antibody; DQA1_HUMAN antibody; FLJ27088 antibody; FLJ27328 antibody; Gluten-sensitive enteropathy (celiac disease) antibody; GSE antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen; DQ alpha 1 chain antibody; HLA class II histocompatibility antigen; DQ(W3) alpha chain antibody; HLA-DCA antibody; HLA-DQA antibody; HLA-DQA1 antibody; HLA-DQA1 major histocompatibility complex; class II; DQ alpha 1 antibody; HLADC histocompatibility type antibody; Immune response antigens HIa; included antibody; leucocyte antigen DQA1 antibody; leukocyte antigen alpha chain antibody; LOC100133678 antibody; LOC100507686 antibody; LOC100509457 antibody; Major histocompatibility complex; class II; DQ alpha 1 antibody; MGC149527 antibody; MHC class II antigen antibody; MHC class II DQA1 antibody; MHC class II HLA-D alpha glycoprotein antibody; MHC class II HLA-DQ alpha 1 antibody; MHC class II surface glycoprotein antibody; MHC HLA-DQ alpha antibody; OTTHUMP00000029141 antibody; OTTHUMP00000176885 antibody; OTTHUMP00000178551 antibody; OTTHUMP00000178552 antibody; OTTHUMP00000233817 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01909
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DQ alpha 1 chain protein (24-213AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DQA1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : beta1 domain MHC class II HLA DPB antibody; class II histocompatibility antigen; DP(W4) beta chain antibody; class II HLA beta chain antibody; DP beta 1 chain antibody; DP(W4) beta chain antibody; DPB1 antibody; DPB1_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen; DP beta 1 chain antibody; HLA class II histocompatibility antigen; DP(W4) beta chain antibody; HLA DP14-beta chain antibody; HLA-DP antibody; HLA-DP histocompatibility type; beta-1 subunit antibody; HLA-DP1B antibody; HLA-DPB antibody; HLA-DPB1 antibody; major histocompatibility complex class II antigen beta chain antibody; major histocompatibility complex; class II; DP beta 1 antibody; MHC class II antigen beta chain antibody; MHC class II antigen DP beta 1 chain antibody; MHC class II antigen DPB1 antibody; MHC class II antigen DPbeta1 antibody; MHC class II HLA-DP-beta-1 antibody; MHC class II HLA-DRB1 antibody; MHC HLA DPB1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04440
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DP beta 1 chain protein (30-225AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DPB1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA-DPA1 antibody; HLA-DP1A antibody; HLASBHLA class II histocompatibility antigen antibody; DP alpha 1 chain antibody; DP(W3) antibody; DP(W4) antibody; HLA-SB alpha chain antibody; MHC class II DP3-alpha antibody; MHC class II DPA1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20036
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DP alpha 1 chain protein (29-222AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DPA1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA-DMA antibody; DMA antibody; RING6HLA class II histocompatibility antigen antibody; DM alpha chain antibody; MHC class II antigen DMA antibody; Really interesting new gene 6 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P28067
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly syntheVolumed MHC class II molec µLes and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DMA
Research Areas : Cardiovasc µLar; Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA class I histocompatibility antigen, Cw-6 alpha chain (MHC class I antigen Cw*6), HLA-C, HLAC
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O78179
Immunogen : Recombinant Human HLA-C protein (25-308AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the presentation of foreign antigens to the immune system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-C
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : HLA class I histocompatibility antigen, B-14 alpha chain (MHC class I antigen B*14), HLA-B, HLAB
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96DW9
Immunogen : Recombinant Human HLA-B protein (25-308AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the presentation of foreign antigens to the immune system
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-B
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BC016235 antibody; Hexokinase domain containing 1 antibody; Hexokinase domain-containing protein 1 antibody; Hkdc1 antibody; HKDC1_HUMAN antibody; Putative hexokinase HKDC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q2TB90
Immunogen : Recombinant Human Putative hexokinase HKDC1 protein (129-427AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HKDC1
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DKFZp686M1669 antibody; Hexokinase 2 antibody; Hexokinase 2 muscle antibody; Hexokinase type II antibody; Hexokinase-2 antibody; HK 2 antibody; HK II antibody; HK2 antibody; HKII antibody; HxK 2 antibody; HxK2 antibody; HXK2_HUMAN antibody; Muscle form hexokinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52789
Immunogen : Recombinant Human Hexokinase-2 protein (334-526AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HK2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BB404130 antibody; Brain form hexokinase antibody; dea antibody; DrHXK1 antibody; EC 2.7.1.1 antibody; Glycolytic enzyme antibody; HEXOKIN antibody; hexokinase I antibody; Hexokinase PI antibody; Hexokinase type I antibody; Hexokinase; tumor isozyme antibody; Hexokinase-1 antibody; Hexokinase-A antibody; HK I antibody; HK1 antibody; HK1 tb antibody; HK1 tc antibody; Hk1-s antibody; HK1-ta antibody; HK1-tb antibody; HK1-tc antibody; HKD antibody; HKI antibody; HMSNR antibody; HXK1 antibody; HXK1_HUMAN antibody; im : 7148527 antibody; mHk1-s antibody; wu : fc09d08 antibody; wu : fc16e02 antibody; wu : fc21e02 antibody; wu : fq14b11 antibody; zgc : 55790 antibody; zgc : 77618 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19367
Immunogen : Recombinant Human Hexokinase-1 protein (13-475AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HK1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HJURP antibody; FAKTS antibody; FLEG1 antibody; URLC9 antibody; Holliday junction recognition protein antibody; 14-3-3-associated AKT substrate antibody; Fetal liver-expressing gene 1 protein antibody; Up-reg µLated in lung cancer 9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NCD3
Immunogen : Recombinant Human Holliday junction recognition protein (1-748AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly syntheVolumed CENPA molec µLes into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HJURP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Histone H2B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Cairina moschata (Muscovy duck)
UniProt ID : P14001
Immunogen : Recombinant Crocodylus niloticus Histone H2B protein (2-93AA)
Raised in : Rabbit
Species Reactivity : Cairina moschata
Tested Applications :
Background : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others