FITC

Volume : 50 µg
Clone Number :
Aliases : c Ki ras2 antibody; c Kirsten ras protein antibody; c-K-ras antibody; c-Ki-ras antibody; Cell µLar c Ki ras2 proto oncogene antibody; Cell µLar transforming proto oncogene antibody; CFC2 antibody; cK Ras antibody; GTPase KRas antibody; K RAS p21 protein antibody; K RAS2A antibody; K RAS2B antibody; K RAS4A antibody; K RAS4B antibody; K-Ras 2 antibody; KI RAS antibody; Ki-Ras antibody; KIRSTEN MURINE SARCOMA VIRUS 2 antibody; Kirsten rat sarcoma 2 viral (v Ki ras2) oncogene homolog antibody; Kirsten rat sarcoma viral oncogene homolog antibody; KRAS antibody; KRAS proto oncogene, GTPase antibody; KRAS1 antibody; KRAS2 antibody; N-terminally processed antibody; NS antibody; NS3 antibody; Oncogene KRAS2 antibody; p21ras antibody; PR310 c K ras oncogene antibody; PR310 cK ras oncogene antibody; RALD antibody; RASK_HUMAN antibody; RASK2 antibody; Transforming protein p21 antibody; v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog antibody; v Ki ras2 Kirsten rat sarcoma viral oncogene homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01116
Immunogen : Recombinant Human GTPase KRas protein (2-168AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the reg µLation of cell proliferation (PubMed : 23698361 PubMed : 22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed : 24623306).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRAS
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : IMB 1 antibody; IMB1 antibody; IMB1_HUMAN antibody; Impnb antibody; Importin 90 antibody; Importin beta 1 antibody; Importin beta 1 subunit antibody; Importin subunit beta-1 antibody; Importin-90 antibody; IPOB antibody; Karyopherin beta 1 antibody; Karyopherin beta 1 subunit antibody; Karyopherin subunit beta-1 antibody; KPNB 1 antibody; Kpnb1 antibody; MGC2155 antibody; MGC2156 antibody; MGC2157 antibody; NTF 97 antibody; NTF97 antibody; NTF97/Importin beta antibody; Nuclear factor P97 antibody; Pore targeting complex 97 kDa subunit antibody; PTAC97 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14974
Immunogen : Recombinant Human Importin subunit beta-1 protein (9-214AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 thro µgh binding to nucleoporin FxFG repeats and the complex is subsequently translocated thro µgh the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is tho µght to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In association with IPO7 mediates the nuclear import of H1 histone. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev. Imports SNAI1 and PRKCI into the nucleus.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KPNB1
Research Areas : Epigenetics and Nuclear Signaling; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ31113 antibody; IMA3_HUMAN antibody; Importin alpha 3 antibody; Importin alpha 4 subunit antibody; Importin alpha Q1 antibody; Importin subunit alpha 3 antibody; Importin subunit alpha-3 antibody; IPO A3 antibody; IPOA 3 antibody; IPOA3 antibody; Karyopherin alpha 4 (importin alpha 3) antibody; Karyopherin alpha 4 antibody; Karyopherin alpha 4 importin alpha 3 antibody; Karyopherin alpha 4 subunit antibody; Karyopherin subunit alpha 4 antibody; Karyopherin subunit alpha-4 antibody; KPNA 4 antibody; Kpna4 antibody; MGC12217 antibody; MGC26703 antibody; OTTHUMP00000213880 antibody; QIP 1 antibody; Qip1 antibody; Qip1 protein antibody; SRP 3 antibody; SRP3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00629
Immunogen : Recombinant Human Importin subunit alpha-3 protein (51-239AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 thro µgh binding to nucleoporin FxFG repeats and the complex is subsequently translocated thro µgh the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is tho µght to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus µL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus µL84 by recognizing a non-classical NLS.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KPNA4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : IMA1_HUMAN antibody; Importin alpha 1 antibody; Importin alpha 2 antibody; Importin alpha 2 subunit antibody; Importin alpha P1 antibody; Importin subunit alpha-1 antibody; IPO A1 antibody; IPOA 1 antibody; IPOA1 antibody; Karyopherin alpha 2 antibody; Karyopherin alpha 2 RAG cohort 1 antibody; Karyopherin alpha 2 subunit antibody; Karyopherin subunit alpha-2 antibody; KPNA2 antibody; KPNA2 protein antibody; Pend µLin antibody; QIP 2 antibody; QIP2 antibody; RAG cohort 1 antibody; RAG cohort protein 1 antibody; RCH 1 antibody; RCH1 antibody; SRP 1 antibody; SRP1 alpha antibody; SRP1 antibody; SRP1-alpha antibody; SRP1alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52292
Immunogen : Recombinant Human Importin subunit alpha-1 protein (2-285AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 thro µgh binding to nucleoporin FxFG repeats and the complex is subsequently translocated thro µgh the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is tho µght to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KPNA2
Research Areas : Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : IMA5_HUMAN antibody; Importin alpha 1 subunit antibody; Importin alpha 5 antibody; Importin alpha S1 antibody; Importin subunit alpha-5; N-terminally processed antibody; IPO A5 antibody; IPOA 5 antibody; IPOA5 antibody; Karyopherin alpha 1 antibody; Karyopherin alpha 1 subunit antibody; Karyopherin subunit alpha-1 antibody; KPNA 1 antibody; KPNA1 antibody; mSRP 1 antibody; mSRP1 antibody; NPI 1 antibody; NPI-1 antibody; NPI1 antibody; Nucleoprotein interactor 1 antibody; RAG cohort protein 2 antibody; RCH 2 antibody; RCH2 antibody; Recombination activating gene cohort 2 antibody; SRP 1 antibody; SRP1 beta antibody; SRP1-beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52294
Immunogen : Recombinant Human Importin subunit alpha-5 protein (8-538AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 thro µgh binding to nucleoporin FxFG repeats and the complex is subsequently translocated thro µgh the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is tho µght to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus µL84 by recognizing a non-classical NLS.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KPNA1
Research Areas : Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KP6 killer toxin antibody; Killer protein 6) [Cleaved into : KP6 killer toxin subunit alpha antibody; VP10); KP6 killer toxin subunit beta antibody; VP12.5)] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Ustilago maydis P6 virus (UmV6) (UmV-P6)
UniProt ID : P16948
Immunogen : Recombinant Ustilago maydis P6 virus KP6 killer toxin protein (28-105AA)
Raised in : Rabbit
Species Reactivity : Ustilago maydis P6 virus
Tested Applications :
Background : This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cell µLar receptors before interaction of the complex with KP6 beta, precipitating cell death.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Kng1 antibody; Kng antibody; Kininogen-1 [Cleaved into : Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P08934
Immunogen : Recombinant Rat Kininogen-1 protein (2-110AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications :
Background : Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coag µLation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects : (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vasc µLar permeability, (4E2) stim µLation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Kng1
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : Histone-lysine N-methyltransferase KMT5C (EC 2.1.1.43) (Lysine N-methyltransferase 5C) (Lysine-specific methyltransferase 5C) (Suppressor of variegation 4-20 homolog 2) (Su(var)4-20 homolog 2) (Suv4-20h2), KMT5C, SUV420H2
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86Y97
Immunogen : Recombinant Human Histone-lysine N-methyltransferase KMT5C protein (235-345aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1 RBL1 and RBL2) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KMT5C
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CGI 85 antibody; CGI85 antibody; Histone-lysine N-methyltransferase KMT5B antibody; Kmt5b antibody; KMT5B_HUMAN antibody; Lysine N-methyltransferase 5B antibody; Lysine-specific methyltransferase 5B antibody; MGC118906 antibody; MGC118909 antibody; MGC21161 antibody; MGC703 antibody; Su(var)4-20 homolog 1 antibody; Suppressor of variegation 4 20 homolog 1 antibody; Suppressor of variegation 4-20 homolog 1 antibody; Suv4-20h1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q4FZB7
Immunogen : Recombinant Human Histone-lysine N-methyltransferase KMT5B protein (100-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Histone methyltransferase that specifically trimethylates \'Lys-20\' of histone H4. H4 \'Lys-20\' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1 RBL1 and RBL2) (By similarity). Plays a role in myogenesis by reg µLating the expression of target genes, such as EID3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KMT5B
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : H4 K20 HMTase antibody; H4 K20 specific histone methyltransferase antibody; H4-K20-HMTase SETD8 antibody; Histone H4 K20 methyltransferase antibody; Histone lysine N methyltransferase H4 lysine 20 specific antibody; Histone-lysine N-methyltransferase SETD8 antibody; Lysine N-methyltransferase 5A antibody; N-lysine methyltransferase SETD8 antibody; Pr SET 7 antibody; Pr SET7 antibody; PR-Set7 antibody; PR/SET domain containing protein 07 antibody; PR/SET domain containing protein 8 antibody; PR/SET domain-containing protein 07 antibody; PR/SET07 antibody; PrSET7 antibody; SET 07 antibody; SET 8 antibody; SET domain containing (lysine methyltransferase) 8 antibody; SET domain containing 8 antibody; SET domain containing lysine methyltransferase 8 antibody; SET domain containing protein 8 antibody; SET domain-containing protein 8 antibody; SET07 antibody; SET8 antibody; SETD 8 antibody; setd8 antibody; SETD8_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQR1
Immunogen : Recombinant Human N-lysine methyltransferase KMT5A protein (136-258AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates \\\'Lys-20\\\' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at \\\'Lys-382\\\', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response reg µLation and a positive role in cell migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KMT5A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : HDCMC04P antibody; Histone lysine N methyltransferase MLL5 antibody; Histone-lysine N-methyltransferase MLL5 antibody; KMT2E antibody; Lysine N methyltransferase 2E antibody; Lysine N-methyltransferase 2E antibody; MGC70452 antibody; Mll5 antibody; MLL5_HUMAN antibody; Myeloid/lymphoid or mixed lineage leukemia 5 (trithorax homolog; Drosophila) antibody; Myeloid/lymphoid or mixed lineage leukemia 5 antibody; Myeloid/lymphoid or mixed lineage leukemia protein 5 antibody; Myeloid/lymphoid or mixed-lineage leukemia protein 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IZD2
Immunogen : Recombinant Human Histone-lysine N-methyltransferase 2E protein (182-316AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Histone methyltransferase that specifically mono- and dimethylates \'Lys-4\' of histone H3 (H3K4me1 and H3K4me2). H3 \'Lys-4\' methylation represents a specific tag for epigenetic transcriptional activation. Key reg µLator of hematopoiesis involved in terminal myeloid differentiation and in the reg µLation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Plays an essential role in retinoic-acid-induced gran µLopoiesis by acting as a coactivator of RAR-alpha (RARA) in target gene promoters. Also acts as an important cell cycle reg µLator, participating in cell cycle reg µLatory network machinery at m µLtiple cell cycle stages. Required to suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells. Overexpression inhibits cell cycle progression, while knockdown induces cell cycle arrest at both the G1 and G2/M phases.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KMT2E
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Developmental biology; Stem cells