FITC

Volume : 50 µg
Clone Number :
Aliases : BRO1 domain and CAAX motif containing antibody; BRO1 domain containing protein antibody; BRO1 domain- and CAAX motif-containing protein antibody; BRO1 domain-containing protein BROX antibody; BROFTI antibody; Brox antibody; BROX_HUMAN antibody; C1orf58 antibody; FLJ32421 antibody; hCG_25336 antibody; RP11-452F19.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5VW32
Immunogen : Recombinant Human BRO1 domain-containing protein BROX protein (288-409AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : extracell µLar exosome
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BROX
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : ATP dependent RNA helicase BRIP1 antibody; ATP-dependent RNA helicase BRIP1 antibody; BACH 1 antibody; BRAC 1 Associated C Terminal Helicase 1 antibody; BRCA 1 Interacting Protein 1 antibody; BRCA1 binding helicase like protein BACH1 antibody; BRCA1 interacting protein C terminal helicase 1 antibody; BRCA1-associated C-terminal helicase 1 antibody; BRCA1-interacting protein 1 antibody; BRCA1-interacting protein C-terminal helicase 1 antibody; BRCA1/BRCA2 associated helicase 1 antibody; BRIP 1 antibody; BRIP1 antibody; FANCJ antibody; FANCJ_HUMAN antibody; Fanconi anemia group J protein antibody; FLJ90232 antibody; MGC126521 antibody; MGC126523 antibody; OF antibody; Protein FACJ antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BX63
Immunogen : Recombinant Human Fanconi anemia group J protein (66-243AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : DNA-dependent ATPase and 5\' to 3\' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRIP1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : BRINP3 antibody; DBCCR1L antibody; DBCCR1L1 antibody; FAM5CBMP/retinoic acid-inducible neural-specific protein 3 antibody; DBCCR1-like protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q76B58
Immunogen : Recombinant Human BMP/retinoic acid-inducible neural-specific protein 3 protein (389-487AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inhibits neuronal cell proliferation by negative reg µLation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRINP3
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : BRINP2 antibody; DBCCR1L2 antibody; FAM5B antibody; KIAA1747BMP/retinoic acid-inducible neural-specific protein 2 antibody; DBCCR1-like protein 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9C0B6
Immunogen : Recombinant Human BMP/retinoic acid-inducible neural-specific protein 2 protein (34-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inhibits neuronal cell proliferation by negative reg µLation of the cell cycle transition.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRINP2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BMP/retinoic acid-inducible neural-specific protein 1 antibody; BRINP1 antibody; DBC1 antibody; DBC1_HUMAN antibody; DBCCR1 antibody; Deleted in bladder cancer protein 1 antibody; Deleted in bladder cancer protein 1 precursor antibody; FAM5A antibody; IB3089A antibody; Protein FAM5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60477
Immunogen : Recombinant Human BMP/retinoic acid-inducible neural-specific protein 1 protein (20-320AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inhibits cell proliferation by negative reg µLation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and reg µLates expression of components of the plasminogen pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRINP1
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : BRD8 antibody; SMAP antibody; SMAP2 antibody; Bromodomain-containing protein 8 antibody; Skeletal muscle abundant protein antibody; Skeletal muscle abundant protein 2 antibody; Thyroid hormone receptor coactivating protein of 120 kDa antibody; TrCP120 antibody; p120 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H0E9
Immunogen : Recombinant Human Bromodomain-containing protein 8 protein (641-859AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stim µLates transcriptional activation by AR/DHTR, ESR1/NR3A1 RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively reg µLate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD8
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism; Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 75 kDa bromodomain protein antibody; BP75 antibody; BRD 7 antibody; BRD7 antibody; BRD7_HUMAN antibody; Bromodomain containing 7 antibody; bromodomain containing protein 7 antibody; Bromodomain-containing protein 7 antibody; CELTIX 1 antibody; CELTIX1 antibody; NAG4 antibody; Protein CELTIX-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NPI1
Immunogen : Recombinant Human Bromodomain-containing protein 7 protein (601-651AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively reg µLating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\'Tyr-216\\\'. Down-reg µLates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-reg µLates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\'Lys-9\\\' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\'Lys-382\\\', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD7
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Brd4 antibody; BRD4-NUT FUSION antibody; BRD4-NUT fusion oncoprotein antibody; BRD4_HUMAN antibody; Bromodomain containing 4 antibody; bromodomain containing protein 4 antibody; Bromodomain-containing protein 4 antibody; CAP antibody; chromosome associated protein antibody; HUNK1 antibody; HUNKI antibody; MCAP antibody; Mitotic chromosome-associated protein antibody; Protein HUNK1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60885
Immunogen : Recombinant Human Bromodomain-containing protein 4 protein (150-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription reg µLation. Remains associated with acetylated chromatin thro µghout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure. During interphase, plays a key role in reg µLating the transcription of signal-inducible genes by associating with the P-TEFb complex and recruiting it to promoters : BRD4 is required to form the transcriptionally active P-TEFb complex by displacing negative reg µLators such as HEXIM1 and 7SKsnRNA complex from P-TEFb, thereby transforming it into an active form that can then phosphorylate the C-terminal domain (CTD) of RNA polymerase II. Promotes phosphorylation of \'Ser-2\' of the C-terminal domain (CTD) of RNA polymerase II. According to a report, directly acts as an atypical protein kinase and mediates phosphorylation of \'Ser-2\' of the C-terminal domain (CTD) of RNA polymerase II; these data however need additional evidences in vivo (PubMed : 22509028). In addition to acetylated histones, also recognizes and binds acetylated RELA, leading to further recruitment of the P-TEFb complex and subsequent activation of NF-kappa-B. Also acts as a reg µLator of p53/TP53-mediated transcription : following phosphorylation by CK2, recruited to p53/TP53 specific target promoters.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD4
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : BRD 3 antibody; Brd3 antibody; BRD3_HUMAN antibody; Bromodomain containing 3 antibody; Bromodomain containing protein 3 antibody; Bromodomain-containing protein 3 antibody; KIAA0043 antibody; Open reading frame X antibody; ORFX antibody; RING3 like gene antibody; RING3-like protein antibody; RING3L antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15059
Immunogen : Recombinant Human Bromodomain-containing protein 3 protein (356-506AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds hyperacetylated chromatin and plays a role in the reg µLation of transcription, probably by chromatin remodeling and interaction with transcription factors. Reg µLates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Reg µLates transcription of the CCND1 gene.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : BR140-like protein antibody; BRD1 antibody; BRD1_HUMAN antibody; BRL antibody; Bromodomain and PHD finger-containing protein 2 antibody; Bromodomain containing 1 antibody; Bromodomain-containing protein 1 antibody; BRPF1 antibody; BRPF2 antibody; DKFZp686F0325 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95696
Immunogen : Recombinant Human Bromodomain-containing protein 1 protein (756-879AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : BRCA1-A complex subunit BRCC36 antibody; BRCA1/BRCA2 containing complex subunit 3 antibody; BRCA1/BRCA2 containing complex subunit 36 antibody; BRCA1/BRCA2-containing complex subunit 3 antibody; BRCA1/BRCA2-containing complex subunit 36 antibody; Brcc3 antibody; BRCC3_HUMAN antibody; BRCC36 antibody; BRISC complex subunit BRCC36 antibody; C6.1A antibody; Chromosome X open reading frame 53 antibody; CXorf53 antibody; Lys-63-specific deubiquitinase BRCC36 antibody; OTTHUMP00000061450 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P46736
Immunogen : Recombinant Human Lys-63-specific deubiquitinase BRCC36 protein (14-316AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Metalloprotease that specifically cleaves \\\'Lys-63\\\'-linked polyubiquitin chains. Does not have activity toward \\\'Lys-48\\\'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes \\\'Lys-63\\\'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes \\\'Lys-63\\\'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a m µLtiprotein complex that specifically cleaves \\\'Lys-63\\\'-linked ubiquitin in various substrates. Mediates the specific \\\'Lys-63\\\'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRCC3
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology