Volume : 50 µg
Clone Number :
Aliases : DKFZP586J0917 antibody; FLJ99588 antibody; HD 7a antibody; HD7 antibody; HD7a antibody; HDAC 7 antibody; HDAC 7A antibody; Hdac7 antibody; HDAC7_HUMAN antibody; HDAC7A antibody; Histone deacetylase 7 antibody; Histone deacetylase 7A antibody; OTTHUMP00000202813 antibody; OTTHUMP00000202814 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WUI4
Immunogen : Recombinant Human Histone deacetylase 7 protein (647-917AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional reg µLation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large m µLtiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively reg µLates the transcriptional repressor activity of FOXP3 (PubMed : 17360565).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HDAC7
Research Areas : Epigenetics and Nuclear Signaling; Cardiovasc µLar; Stem cells