HRP labelled

Volume : 50 µL
Clone Number :
Aliases : HMGXB4 antibody; HMG2L1 antibody; HMGBCG antibody; HMG domain-containing protein 4 antibody; HMG box-containing protein 4 antibody; High mobility group protein 2-like 1 antibody; Protein HMGBCG antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µgU5
Immunogen : Peptide sequence from Human HMG domain-containing protein 4 protein (489-509AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Negatively reg µLates Wnt/beta-catenin signaling during development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGXB4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DKFZp686E20226 antibody; FLJ42187 antibody; High mobility group nucleosomal binding domain 3 antibody; High mobility group nucleosome-binding domain-containing protein 3 antibody; HMGN3 antibody; HMGN3_HUMAN antibody; OTTHUMP00000016772 antibody; OTTHUMP00000016773 antibody; PNAS 24 antibody; PNAS 25 antibody; PNAS24 antibody; PNAS25 antibody; Thyroid hormone receptor interacting protein 7 antibody; Thyroid receptor-interacting protein 7 antibody; TR-interacting protein 7 antibody; TRIP 7 antibody; TRIP-7 antibody; TRIP7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15651
Immunogen : Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds to nucleosomes, reg µLating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both ins µLin and glucagon levels and mod µLates the expression of pancreatic genes involved in ins µLin secretion. Reg µLates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Reg µLates the expression of SLC6A9, a glycine transporter which reg µLates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in oc µLar development and astrocyte function (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGN3
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial) antibody; 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 antibody; 3 hydroxy 3 methylglutaryl coenzyme A synthase antibody; 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody; HMCS2_HUMAN antibody; HMG CoA synthase antibody; HMG-CoA synthase antibody; HMGCS 2 antibody; HMGCS2 antibody; Hydroxymethylglutaryl CoA synthase antibody; Hydroxymethylglutaryl CoA synthase mitochondrial antibody; Hydroxymethylglutaryl-CoA synthase antibody; mitochondrial antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54868
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA synthase, mitochondrial protein (426-508AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCS2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble) antibody; 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody; cytoplasmic antibody; EC 2.3.3.10 antibody; HMCS1_HUMAN antibody; HMG CoA synthase antibody; HMG-CoA synthase antibody; HMGCS antibody; HMGCS1 antibody; Hydroxymethylglutaryl CoA synthase, cytoplasmic antibody; Hydroxymethylglutaryl-CoA synthase antibody; MGC90332 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01581
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA synthase, cytoplasmic protein (360-520AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCS1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl CoA reductase antibody; 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody; 3 hydroxymethylglutaryl CoA reductase antibody; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody; 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody; 3H3M antibody; HMDH_HUMAN antibody; HMG CoA reductase antibody; HMG CoAR antibody; HMG-CoA reductase antibody; Hmgcr antibody; Hydroxymethylglutaryl CoA reductase antibody; LDLCQ3 antibody; MGC103269 antibody; Red antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04035
Immunogen : Recombinant Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCR
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HMGCLL1 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase antibody; cytoplasmic antibody; EC 4.1.3.4 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 antibody; Endoplasmic retic µLum 3-hydroxy-3-methylglutaryl-CoA lyase antibody; er-cHL antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TB92
Immunogen : Recombinant Human 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic protein (2-340AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCLL1
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase), HMGCL
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35914
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial protein (28-325aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as reg µLators of metabolism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCL
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : HMGB4 antibody; High mobility group protein B4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WW32
Immunogen : Recombinant Human High mobility group protein B4 protein (1-186AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : chromosomal protein; Nonhistone; HMG4 antibody; High mobility group (nonhistone chromosomal) protein 4 antibody; High mobility group box 3 antibody; High mobility group protein 2a antibody; High mobility group protein 4 antibody; High mobility group protein B3 antibody; High mobility group protein HMG4 antibody; HMG 4 antibody; HMG-2a antibody; HMG-4 antibody; HMG2A antibody; HMGB 3 antibody; Hmgb3 antibody; HMGB3_HUMAN antibody; MGC90319 antibody; Non histone chromosomal protein antibody; Nonhistone chromosomal protein HMG4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15347
Immunogen : Recombinant Human High mobility group protein B3 protein (1-103AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively reg µLates B-cell and myeloid cell differentiation. In hematopoietic stem cells may reg µLate the balance between self-renewal and differentiation. Involved in negative reg µLation of canonical Wnt signaling (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : C80539 antibody; High mobility group (nonhistone chromosomal) protein 2 antibody; High mobility group box 2 antibody; High mobility group protein 2 antibody; High mobility group protein B2 antibody; HMG 2 antibody; HMG B2 antibody; HMG-2 antibody; HMG2 antibody; HMGB2 antibody; HMGB2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26583
Immunogen : Recombinant Human High mobility group protein B2 protein (43-185AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant reg µLatory sequences into close proximity (PubMed : 7797075, PubMed : 11909973, PubMed : 19522541 PubMed : 18413230, PubMed : 19965638, PubMed : 20123072). Involved in V(D)J recombination by acting as a cofactor of the RAG complex : acts by stim µLating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a promiscuous immunogenic DNA/RNA sensor which cooperates with subsequent discriminative sensing by specific pattern recognition receptors (By similarity). In the extracell µLar compartment acts as a chemokine. Promotes proliferation and migration of endothelial cells implicating AGER/RAGE (PubMed : 19811285). Has antimicrobial activity in gastrointestinal epithelial tissues (PubMed : 23877675). Involved in inflammatory response to antigenic stim µLus coupled with proinflammatory activity (By similarity). Involved in mod µLation of neurogenesis probably by reg µLation of neural stem proliferation (By similarity). Involved in artic µLar cartilage surface maintenance implicating LEF1 and the Wnt/beta-catenin pathway (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility group protein 1) (HMG-1), Hmgb1 Hmg-1 Hmg1
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P63159
Immunogen : Recombinant Rat High mobility group protein B1 protein (2-18aa)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : M µLtifunctional redox sensitive protein with various roles in different cell µLar compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molec µLar pattern (DAMP) molec µLe that amplifies immune responses during tissue injury. Released to the extracell µLar environment can bind DNA, nucleosomes, IL-1 beta, CXCL12, AGER isoform 2/sRAGE, lipopolysaccharide (LPS) and lipoteichoic acid (LTA), and activates cells thro µgh engagement of m µLtiple surface receptors. In the extracell µLar compartment f µLly reduced HMGB1 (released by necrosis) acts as a chemokine, dis µLfide HMGB1 (actively secreted) as a cytokine, and s µLfonyl HMGB1 (released from apoptotic cells) promotes immunological tolerance (PubMed : 23519706, PubMed : 23446148, PubMed : 23994764, PubMed : 25048472). Has proangiogenic activity. May be involved in platelet activation. Binds to phosphatidylserine and phosphatidylethanolamide (PubMed : 11154118). Bound to RAGE mediates signaling for neuronal outgrowth (PubMed : 1885601 PubMed : 2461949, PubMed : 7592757, PubMed : 12183440). May play a role in accum µLation of expanded polyglutamine (polyQ) proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Hmgb1
Research Areas : Others