HRP labelled

Volume : 50 µL
Clone Number :
Aliases : FLH21957 antibody; FLJ10410 antibody; FLJ20373 antibody; FLJ90111 antibody; Hepatocyte progenitor kinase like/germinal center kinase like kinase antibody; HGK antibody; HPK/GCK like kinase antibody; HPK/GCK like kinase HGK antibody; HPK/GCK-like kinase HGK antibody; KIAA0687 antibody; M4K4_HUMAN antibody; MAP4K4 antibody; MAPK/ERK kinase kinase kinase 4 antibody; MEK kinase kinase 4 antibody; MEKKK 4 antibody; MEKKK4 antibody; Mitogen activated protein kinase kinase kinase kinase 4 antibody; Mitogen-activated protein kinase kinase kinase kinase 4 antibody; Nck interacting kinase antibody; Nck-interacting kinase antibody; NIK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95819
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 4 protein (866-1104AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP4K4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B lymphocyte serine/threonine protein kinase antibody; B lymphocyte serine/threonine-protein kinase antibody; BL44 antibody; GC kinase antibody; GCK antibody; Germinal center kinase antibody; germinal centre kinase (GC kinase) antibody; M4K2_HUMAN antibody; Map4k2 antibody; MAPK/ERK kinase kinase kinase 2 antibody; MEK kinase kinase 2 antibody; MEKKK 2 antibody; Mitogen activated protein kinase kinase kinase kinase 2 antibody; Mitogen-activated protein kinase kinase kinase kinase 2 antibody; Rab8 interacting protein antibody; Rab8 interacting protein, formerly antibody; Rab8-interacting protein antibody; RAB8IP antibody; RAB8IP, formerly antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q12851
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 2 protein (386-469AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway. Required for the efficient activation of JNKs by TRAF6-dependent stim µLi, including pathogen-associated molec µLar patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin. To a lesser degree, IL-1 and engagement of CD40 also stim µLate MAP4K2-mediated JNKs activation. The requirement for MAP4K2/GCK is most pronounced for LPS signaling, and extends to LPS stim µLation of c-Jun phosphorylation and induction of IL-8. Enhances MAP3K1 oligomerization, which may relieve N-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. Mediates also the SAP/JNK signaling pathway and the p38 MAPKs signaling pathway thro µgh activation of the MAP3Ks MAP3K10/MLK2 and MAP3K11/MLK3. May play a role in the reg µLation of vesicle targeting or fusion. reg µLation of vesicle targeting or fusion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP4K2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DKFZp779A1753 antibody; MAP-4 antibody; MAP4 antibody; MAP4_HUMAN antibody; MGC8617 antibody; Microtub µLe associated protein 4 antibody; Microtub µLe-associated protein 4 antibody; OTTHUMP00000210723 antibody; OTTHUMP00000210725 antibody; OTTHUMP00000210727 antibody; OTTHUMP00000210730 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P27816
Immunogen : Recombinant Human Microtub µLe-associated protein 4 protein (575-818AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-neuronal microtub µLe-associated protein. Promotes microtub µLe assembly.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP4
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : M3K9_HUMAN antibody; Map3k9 antibody; MEKK9 antibody; Mitogen activated protein kinase kinase kinase 9 antibody; Mitogen-activated protein kinase kinase kinase 9 antibody; Mixed lineage kinase 1 (tyr and ser/thr specificity) antibody; Mixed lineage kinase 1 antibody; MLK1 antibody; PRKE1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P80192
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 9 protein (864-1098AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cell µLar responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade thro µgh the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway reg µLates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K9
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AURA2 antibody; c COT antibody; Cancer Osaka thyroid oncogene antibody; CCOT antibody; COT antibody; COT proto oncogene serine/threonine protein kinase antibody; EST antibody; ESTF antibody; Ewing sarcoma transformant antibody; FLJ10486 antibody; M3K8_HUMAN antibody; MAP3K 8 antibody; MAP3K8 antibody; MEKK8 antibody; Mitogen activated protein kinase kinase kinase 8 antibody; Mitogen-activated protein kinase kinase kinase 8 antibody; Proto oncogene cCot antibody; Proto-oncogene c-Cot antibody; Serine/threonine protein kinase cot antibody; Serine/threonine-protein kinase cot antibody; TPL 2 antibody; TPL-2 antibody; TPL2 antibody; Tumor progression locus 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P41279
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 8 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the reg µLation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection thro µgh negative reg µLation of type I interferon (IFN) production. In vitro, activates MAPK/ERK pathway in response to IL1 in an IRAK1-independent manner, leading to up-reg µLation of IL8 and CCL4. Transduces CD40 and TNFRSF1A signals that activate ERK in B-cells and macrophages, and thus may play a role in the reg µLation of immunoglob µLin production. May also play a role in the transduction of TNF signals that activate JNK and NF-kappa-B in some cell types. In adipocytes, activates MAPK/ERK pathway in an IKBKB-dependent manner in response to IL1B and TNF, but not ins µLin, leading to induction of lipolysis. Plays a role in the cell cycle. Isoform 1 shows some transforming activity, altho µgh it is much weaker than that of the activated oncogenic variant.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K8
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : MAP3K7CL antibody; C21orf7 antibody; TAK1LMAP3K7 C-terminal-like protein antibody; TAK1-like protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P57077
Immunogen : Recombinant Human MAP3K7 C-terminal-like protein (1-142AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K7CL
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : M3K7_HUMAN antibody; MAP3K 7 antibody; Map3k7 antibody; MEKK7 antibody; Mitogen activated protein kinase kinase kinase 7 antibody; Mitogen-activated protein kinase kinase kinase 7 antibody; TAK1 antibody; TGF beta activated kinase 1 antibody; TGF-beta-activated kinase 1 antibody; TGF1a antibody; Transforming growth factor beta activated kinase 1 antibody; Transforming growth factor-beta-activated kinase 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43318
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 7 protein (101-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cell µLar responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade thro µgh the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1 MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1 but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K7
Research Areas : Cancer; Cardiovasc µLar; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Apoptosis signal reg µLating kinase 2 antibody; Apoptosis signal-reg µLating kinase 2 antibody; ASK2 antibody; EC 2.7.11.25 antibody; M3K6_HUMAN antibody; MAP3K6 antibody; MAPKKK6 antibody; MEKK6 antibody; MGC125653 antibody; MGC20114 antibody; Mitogen-activated protein kinase kinase kinase 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95382
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 6 protein (905-990AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K6
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Apoptosis signal reg µLating kinase 1 antibody; Apoptosis signal-reg µLating kinase 1 antibody; ASK 1 antibody; ASK-1 antibody; ASK1 antibody; M3K5 antibody; M3K5_HUMAN antibody; MAP/ERK kinase kinase 5 antibody; MAP3K5 antibody; MAPK/ERK kinase kinase 5 antibody; MAPKKK5 antibody; MEK kinase 5 antibody; MEKK 5 antibody; MEKK5 antibody; Mitogen activated protein kinase kinase kinase 5 antibody; Mitogen-activated protein kinase kinase kinase 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99683
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 5 protein (363-431AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cell µLar responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway thro µgh mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS). Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade thro µgh the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1 MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs). Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K5
Research Areas : Cardiovasc µLar; Cell biology

Volume : 50 µg
Clone Number :
Aliases : dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody; FLJ42439 antibody; KIAA0213 antibody; M3K4_HUMAN antibody; MAP three kinase 1 antibody; MAP/ERK kinase kinase 4 antibody; MAP3K4 antibody; MAPK/ERK kinase kinase 4 antibody; MAPKKK4 antibody; MEK kinase 4 antibody; MEKK 4 antibody; MEKK4 antibody; Mitogen-activated protein kinase kinase kinase 4 antibody; MTK1 antibody; predicted protein of HQ0412 antibody; PRO0412 antibody; RP3-473J16.4 antibody; SSK2/SSK22 MAP kinase kinase kinase; yeast; homolog of antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y6R4
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 4 protein (53-145AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K4
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dJ862P8.3 antibody; KIAA1804 antibody; M3KL4_HUMAN antibody; Mitogen activated protein kinase kinase kinase antibody; Mitogen-activated protein kinase kinase kinase MLK4 antibody; Mixed lineage kinase 4 antibody; MLK 4 antibody; Mlk4 antibody; RP5 862P8.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5TCX8
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 21 protein (640-794AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Negative reg µLator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K21
Research Areas : Signal transduction