ITGAL Monoclonal Antibody FITC Conjugated

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P20701
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : 4A122 reacts with CD11a, a 180 kDa molec µLe. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and gran µLocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate.1. Schlossman. S et al. (1995) Leucocyte Typing V : White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16 : 479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7 : 99.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology;Signal transduction?Stem cells