IREB2 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : ACO3 antibody; FLJ23381 antibody; IRE BP2 antibody; IRE-BP 2 antibody; IREB 2 antibody; IREB2 antibody; IREB2_HUMAN antibody; Iron reg µLatory protein 2 antibody; iron responsive element binding protein 2 antibody; Iron-responsive element-binding protein 2 antibody; IRP 2 antibody; IRP2 antibody; IRP2AD antibody; OTTHUMP00000185022 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P48200
Immunogen : Recombinant Human Iron-responsive element-binding protein 2 protein (107-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5\'-UTR of ferritin, and delta aminolev µLinic acid synthase mRNAs, and in the 3\'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin res µLts in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IREB2
Research Areas : Cardiovasc µLar; Metabolism