IRF9 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : IFN alpha responsive transcription factor subunit antibody; IFN-alpha-responsive transcription factor subunit antibody; Interferon reg µLatory factor 9 antibody; interferon stim µLated transcription factor 3 antibody; Interferon-stim µLated gene factor 3 gamma antibody; interferon-stim µLated transcription factor 3, gamma 48kDa antibody; IRF 9 antibody; IRF-9 antibody; Irf9 antibody; IRF9_HUMAN antibody; ISGF 3 gamma antibody; ISGF-3 gamma antibody; ISGF3 antibody; ISGF3 p48 subunit antibody; ISGF3G antibody; OTTHUMP00000164692 antibody; OTTHUMP00000164693 antibody; p48 antibody; Transcriptional reg µLator ISGF3 subunit gamma antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00978
Immunogen : Recombinant Human Interferon reg µLatory factor 9 protein (44-180AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1 : STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stim µLated response element (ISRE) to activate the transcription of interferon stim µLated genes, which drive the cell in an antiviral state.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF9
Research Areas : Epigenetics and Nuclear Signaling; Immunology