ITGA5 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08648
Immunogen : Recombinant Human Integrin alpha-5 protein (220-472AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGA5 : ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA5
Research Areas : Signal transduction; Stem cells