KDM4A Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : JHDM3A antibody; JmjC domain containing histone demethylation protein 3A antibody; JmjC domain-containing histone demethylation protein 3A antibody; JMJD2 antibody; JMJD2A antibody; jumonji C domain containing histone demethylase 3A antibody; Jumonji domain containing 2 antibody; Jumonji domain containing 2A antibody; Jumonji domain containing protein 2A antibody; Jumonji domain-containing protein 2A antibody; KDM4A antibody; KDM4A_HUMAN antibody; KIAA0677 antibody; Lysine (K) specific demethylase 4A antibody; Lysine-specific demethylase 4A antibody; TDRD14A antibody; Tudor domain containing 14A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75164
Immunogen : Recombinant Human Lysine-specific demethylase 4A protein (127-364AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Histone demethylase that specifically demethylates \'Lys-9\' and \'Lys-36\' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-4\', H3 \'Lys-27\' nor H4 \'Lys-20\'. Demethylates trimethylated H3 \'Lys-9\' and H3 \'Lys-36\' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1 respectively.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KDM4A
Research Areas : Epigenetics and Nuclear Signaling