KEAP1 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : Cytosolic inhibitor of Nrf2 antibody; INrf 2 antibody; INrf2 antibody; Keap 1 antibody; KEAP1 antibody; KEAP1_HUMAN antibody; Kelch like ECH associated protein 1 antibody; Kelch like family member 19 antibody; Kelch like protein 19 antibody; Kelch-like ECH-associated protein 1 antibody; Kelch-like protein 19 antibody; KIAA0132 antibody; KLHL 19 antibody; KLHL19 antibody; MGC10630 antibody; MGC1114 antibody; MGC20887 antibody; MGC4407 antibody; MGC9454 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14145
Immunogen : Recombinant Human Kelch-like ECH-associated protein 1 protein (1-624AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by C µL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus res µLting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KEAP1
Research Areas : Epigenetics and Nuclear Signaling