IST1 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : hIST1 antibody; Increased sodium tolerance 1 antibody; Increased sodium tolerance 1 homolog antibody; IST1 homolog antibody; IST1_HUMAN antibody; KIAA0174 antibody; MAPK activating protein PM28 antibody; MGC117220 antibody; MGC128433 antibody; Putative MAPK-activating protein PM28 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53990
Immunogen : Recombinant Human IST1 homolog protein (172-284AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed : 19129479, PubMed : 19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex : IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtub µLe severing (PubMed : 26040712). Reg µLates early endosomal tub µLation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed : 23897888).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IST1
Research Areas : Cell biology