KDM6A Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) antibody; bA386N14.2 antibody; bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX antibody; DKFZp686A03225 antibody; Histone demethylase UTX antibody; KABUK2 antibody; Kdm6a antibody; KDM6A_HUMAN antibody; Lysine (K) specific demethylase 6A antibody; Lysine K specific demethylase 6A antibody; Lysine specific demethylase 6A ubiquitously transcribed tetratricopeptide repeat gene X chromosome antibody; Lysine-specific demethylase 6A antibody; MGC141941 antibody; Ubiquitously transcribed tetratricopeptide repeat X chromosome antibody; Ubiquitously transcribed tetratricopeptide repeat protein X linked antibody; Ubiquitously transcribed TPR gene on the X chromosome antibody; Ubiquitously transcribed TPR protein on the X chromosome antibody; Ubiquitously transcribed X chromosome tetratricopeptide repeat protein antibody; Ubiquitously-transcribed TPR protein on the X chromosome antibody; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein antibody; UTX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15550
Immunogen : Recombinant Human Lysine-specific demethylase 6A protein (620-749AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Histone demethylase that specifically demethylates \'Lys-27\' of histone H3, thereby playing a central role in histone code (PubMed : 17851529, PubMed : 17713478, PubMed : 17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 \'Lys-27\' (PubMed : 17851529, PubMed : 17713478, PubMed : 17761849). Plays a central role in reg µLation of posterior development, by reg µLating HOX gene expression (PubMed : 17851529). Demethylation of \'Lys-27\' of histone H3 is concomitant with methylation of \'Lys-4\' of histone H3, and reg µLates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed : 17761849).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KDM6A
Research Areas : Epigenetics and Nuclear Signaling