KDM6B Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Histone demethylase JMJD3 antibody; JmjC domain containing protein 3 antibody; JmjC domain-containing protein 3 antibody; Jumonji D3 antibody; Jumonji domain containing 3 antibody; Jumonji domain containing 3 histone lysine demethylase antibody; Jumonji domain containing protein 3 antibody; Jumonji domain-containing protein 3 antibody; Kdm6b antibody; KDM6B_HUMAN antibody; KIAA0346 antibody; Lysine demethylase 6B antibody; Lysine K specific demethylase 6B antibody; Lysine specific demethylase 6B antibody; Lysine-specific demethylase 6B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15054
Immunogen : Recombinant Human Lysine-specific demethylase 6B protein (1530-1682AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Histone demethylase that specifically demethylates \'Lys-27\' of histone H3, thereby playing a central role in histone code (PubMed : 17825402, PubMed : 17851529, PubMed : 17713478, PubMed : 18003914). Demethylates trimethylated and dimethylated H3 \'Lys-27\' (PubMed : 17825402, PubMed : 17851529, PubMed : 17713478, PubMed : 18003914). Plays a central role in reg µLation of posterior development, by reg µLating HOX gene expression (PubMed : 17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by reg µLating gene expression and macrophage differentiation (PubMed : 17825402).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KDM6B
Research Areas : Epigenetics and Nuclear Signaling