KIF14 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : KIAA0042 antibody; KIF 14 antibody; KIF14 antibody; KIF14_HUMAN antibody; Kinesin Family Member 14 antibody; Kinesin like protein KIF14 antibody; Kinesin-like protein KIF14 antibody; MGC142302 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15058
Immunogen : Recombinant Human Kinesin-like protein KIF14 protein (261-531AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Microtub µLe motor protein that binds to microtub µLes with high affinity thro µgh each tub µLin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed : 24784001 PubMed : 16648480). During cytokinesis, targets to central spindle and midbody thro µgh its interaction with PRC1 and CIT respectively (PubMed : 16431929). Reg µLates cell growth thro µgh reg µLation of cell cycle progression and cytokinesis (PubMed : 24854087). During cell cycle progression acts thro µgh SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, res µLting in positive reg µLation of cyclins, including CCNE1 CCND1 and CCNB1 (PubMed : 24854087). During late neurogenesis, reg µLates the cerebellar, cerebral cortex and olfactory b µLb development thro µgh reg µLation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed : 15843429). Reg µLates cell spreading, focal adhesion dynamics, and cell migration thro µgh its interaction with RADIL res µLting in reg µLation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtub µLes (PubMed : 23209302).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KIF14
Research Areas : Tags & Cell Markers; Signal transduction