ITPR1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : 4 antibody; 5-trisphosphate receptor antibody; 5-trisphosphate receptor type 1 antibody; DKFZp313E1334 antibody; DKFZp313N1434 antibody; inositol 1 4 5 triphosphate receptor type 1 antibody; Inositol 1 4 5 trisphosphate Receptor Type 1 antibody; Inositol 1 antibody; InsP3R1 antibody; IP3 antibody; IP3 receptor antibody; IP3 receptor isoform 1 antibody; IP3R 1 antibody; IP3R antibody; IP3R1 antibody; ITPR 1 antibody; Itpr1 antibody; ITPR1_HUMAN antibody; SCA15 antibody; SCA16 antibody; SCA29 antibody; Type 1 inositol 1 4 5 trisphosphate receptor antibody; Type 1 inositol 1 antibody; Type 1 InsP3 receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14643
Immunogen : Recombinant Human Inositol 14,5-trisphosphate receptor type 1 protein (1707-1966AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Intracell µLar channel that mediates calcium release from the endoplasmic retic µLum following stim µLation by inositol 14,5-trisphosphate (PubMed : 27108797). Involved in the reg µLation of epithelial secretion of electrolytes and fluid thro µgh the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITPR1
Research Areas : Cancer; Metabolism; Signal transduction