KLF1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : CDAN4 antibody; EKLF antibody; EKLF PEN antibody; Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) antibody; Erythroid krueppel-like transcription factor antibody; Erythroid Kruppel like factor antibody; Erythroid specific transcription factor EKLF antibody; HBFQTL6 antibody; Human erythroid-specific transcription factor EKLF mRNA complete cds antibody; INLU antibody; Klf1 antibody; KLF1_HUMAN antibody; Krueppel-like factor 1 antibody; Kruppel like factor 1 (erythroid) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13351
Immunogen : Recombinant Human Krueppel-like factor 1 protein (1-362AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription reg µLator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual reg µLator of fetal-to-ad µLt globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most ad µLts, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLF1
Research Areas : Epigenetics and Nuclear Signaling