KMT5B Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : CGI 85 antibody; CGI85 antibody; Histone-lysine N-methyltransferase KMT5B antibody; Kmt5b antibody; KMT5B_HUMAN antibody; Lysine N-methyltransferase 5B antibody; Lysine-specific methyltransferase 5B antibody; MGC118906 antibody; MGC118909 antibody; MGC21161 antibody; MGC703 antibody; Su(var)4-20 homolog 1 antibody; Suppressor of variegation 4 20 homolog 1 antibody; Suppressor of variegation 4-20 homolog 1 antibody; Suv4-20h1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q4FZB7
Immunogen : Recombinant Human Histone-lysine N-methyltransferase KMT5B protein (100-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Histone methyltransferase that specifically trimethylates \'Lys-20\' of histone H4. H4 \'Lys-20\' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1 RBL1 and RBL2) (By similarity). Plays a role in myogenesis by reg µLating the expression of target genes, such as EID3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KMT5B
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction