KLHL12 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : C3IP1 antibody; C µL3 interacting protein 1 antibody; C µL3-interacting protein 1 antibody; DKIR antibody; DKIR homolog antibody; FLJ27152 antibody; hDKIR antibody; Kelch like 12 (Drosophila) antibody; Kelch like 12 antibody; Kelch like 12 variant antibody; Kelch like protein 12 antibody; Kelch like protein C3IP1 antibody; kelch-like family member 12 antibody; Kelch-like protein 12 antibody; KLH12_HUMAN antibody; KLHL 12 antibody; klhl12 antibody; OTTHUMP00000038799 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q53G59
Immunogen : Recombinant Human Kelch-like protein 12 protein (1-220AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-specific adapter of a BCR (BTB-C µL3-RBX1) E3 ubiquitin ligase complex that acts as a negative reg µLator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by reg µLating the Volume of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division : BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative reg µLator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL12
Research Areas : Others