KANK2 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : KANK2 antibody; ANKRD25 antibody; KIAA1518 antibody; MXRA3 antibody; SIP antibody; KN motif and ankyrin repeat domain-containing protein 2 antibody; Ankyrin repeat domain-containing protein 25 antibody; Matrix-remodeling-associated protein 3 antibody; SRC-1-interacting protein antibody; SIP antibody; SRC-interacting protein antibody; SRC1-interacting protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q63ZY3
Immunogen : Recombinant Human KN motif and ankyrin repeat domain-containing protein 2 protein (410-585AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in transcription reg µLation by sequestering nuclear receptor coactivators, such as NCOA1 NCOA2 and NCOA3, in the cytoplasm; the function is dereg µLated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed : 24671081). May be involved in the control of cytoskeleton formation by reg µLating actin polymerization. Involved in reg µLation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stim µLi lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed : 22371500). May be involved in promotion of cell proliferation (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KANK2
Research Areas : Others