KDM1B Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : amine oxidase (flavin containing) domain 1 antibody; amine oxidase, flavin containing 1 antibody; AOF1 antibody; bA204B7.3 antibody; C6orf193 antibody; dJ298J15.2 antibody; Flavin-containing amine oxidase domain-containing protein 1 antibody; FLJ33898 antibody; FLJ34109 antibody; FLJ43328 antibody; KDM1B antibody; KDM1B_HUMAN antibody; LSD2 antibody; lysine (K)-specific demethylase 1B antibody; Lysine-specific demethylase 2 antibody; Lysine-specific histone demethylase 1B antibody; Lysine-specific histone demethylase 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NB78
Immunogen : Recombinant Human Lysine-specific histone demethylase 1B protein (451-544AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Histone demethylase that demethylates \'Lys-4\' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated \'Lys-4\' of histone H3. Has no effect on tri-methylated \'Lys-4\', mono-, di- or tri-methylated \'Lys-9\', mono-, di- or tri-methylated \'Lys-27\', mono-, di- or tri-methylated \'Lys-36\' of histone H3, or on mono-, di- or tri-methylated \'Lys-20\' of histone H4 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KDM1B
Research Areas : Epigenetics and Nuclear Signaling