APOBEC3D Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : A3D antibody; ABC3D_HUMAN antibody; APOBEC3D antibody; APOBEC3DE antibody; APOBEC3E antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody; ARP6 antibody; bK150C2.9 antibody; BK150C2.9 protein antibody; DNA dC >dU editing enzyme APOBEC 3D antibody; DNA dC->dU-editing enzyme APOBEC-3D antibody; hCG_41704 antibody; HCG41704; isoform CRA_b antibody; Probable DNA dC->dU-editing enzyme APOBEC-3D antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96AK3
Immunogen : Recombinant Human DNA dC->dU-editing enzyme APOBEC-3D protein (250-371AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The res µLtant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : APOBEC3D
Research Areas : Epigenetics and Nuclear Signaling; Cell biology