LGR6 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : FLJ14471 antibody; Gonadotropin receptor antibody; GPCR antibody; Leucine rich repeat containing G protein coupled receptor 6 antibody; Leucine-rich repeat-containing G-protein coupled receptor 6 antibody; Lgr6 antibody; LGR6_HUMAN antibody; VTS20631 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9HBX8
Immunogen : Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of m µLtipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1 RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracell µLar Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LGR6
Research Areas : Signal transduction