ING4 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Brain my036 protein antibody; Candidate tumor suppressor p33 ING 1 homolog antibody; Candidate tumor suppressor p33 ING1 homolog antibody; D6Wsu147e antibody; D6Xrf92 antibody; ING 1 like protein antibody; ING 4 antibody; ING1 like protein antibody; ING4 antibody; ING4_HUMAN antibody; Inhibitor of growth family member 4 antibody; Inhibitor of growth family member 4 long isoform antibody; Inhibitor of growth protein 4 antibody; MGC12557 antibody; my036 antibody; p29 ING 4 antibody; p29 ING4 antibody; p29ING4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UNL4
Immunogen : Recombinant Human Inhibitor of growth protein 4 protein (75-249AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the b µLk of histone H4 acetylation in vivo. Thro µgh chromatin acetylation it may function in DNA replication. May inhibit tumor progression by mod µLating the transcriptional output of signaling pathways which reg µLate cell proliferation. Can suppress brain tumor angiogenesis thro µgh transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ING4
Research Areas : Epigenetics and Nuclear Signaling; Cancer