KRT8 (Ab 74) Antibody

Volume : 100 µL
Clone Number :
Aliases : CARD2 antibody; CK 8 antibody; CK-8 antibody; CK8 antibody; CYK8 antibody; CYKER antibody; Cytokeratin endo A antibody; Cytokeratin-8 antibody; DreK8 antibody; EndoA antibody; K2C8 antibody; K2C8_HUMAN antibody; K8 antibody; Keratin 8 antibody; Keratin type II cytoskeletal 8 antibody; Keratin; type II cytoskeletal 8 antibody; Keratin-8 antibody; KO antibody; Krt 2.8 antibody; KRT8 antibody; MGC118110 antibody; MGC174782 antibody; MGC53564 antibody; MGC85764 antibody; sb : cb186 antibody; Type-II keratin Kb8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05787
Immunogen : Peptide sequence around aa.72~76 (L-L-S-P-L) derived from Human Keratin 8 (CK8).
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF : 1 : 100-1 : 200
Background : Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-Volumed filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cell µLar structural integrity and also functions in signal transduction and cell µLar differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Nakamichi I, et al. (2002) Mol Biol Cell; 13(10) : 3441-3451.
Prochasson P, et al. (2002) Nucleic Acids Res; 30(15) : 3312-3322.
Pankov R, et al. (1994) Proc Natl Acad Sci U S A; 91(3) : 873-877.
Thorey IS, et al. (1993) Mol Cell Biol; 13(11) : 6742-6751.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRT8
Research Areas : Cancer;Signal transduction