Iduronate 2 sulfatase antibody

Volume : 100 µg
Purification : Protein A+G purification
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Mouse
Clonality : monoclonal
Clone ID : 2D2
Isotype : IgG1
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Iduronate 2-s µLfatase (IDS) is required for the lysosomal degradation of heparan s µLfate and dermatan s µLfate. Mutations causing IDS deficiency in humans res µLt in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is syntheVolumed as two precursor forms of 76 and 90 kDa that are converted, thro µgh a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID : 10838181).
Immunogen : iduronate 2-s µLfatase
Aliases : IDS, iduronate 2 s µLfatase, Idurs µLfase
Observed MW : 76 kDa, 55 kDa
Uniprot ID : P22304
Reactivity : Human
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500-1 : 1000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID : 3423
Research Area : Cardiovasc µLar, Metabolism