IFITM2 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against m µLtiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesic µLar stomatitis virus(VSV). Can inhibit : influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP12-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
Immunogen : interferon induced transmembrane protein 2
Aliases : DSPA2c, IFITM2
Observed MW : 15kd
Uniprot ID : Q01629
Reactivity : Human
Application : ELISA, IP, IHC, IF, WB
Recommended dilution : WB : 1 : 500-1 : 2000; IP : 1 : 200-1 : 1000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID : 10581
Research Area : Immunology