JUN antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stim µLation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed : 24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed : 24623306).
Immunogen : jun oncogene
Aliases : Activator protein 1 AP 1 AP1 c Jun, JUN, jun oncogene, P39, Proto oncogene c Jun, Transcription factor AP 1
Observed MW : 39 kDa
Uniprot ID : P05412
Reactivity : Human, Mouse
Application : ELISA, WB, IF, IHC
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200; IF : 1 : 10-1 : 100
Gene ID : 3725
Research Area : Signal Transduction, Metabolism, Cardiovasc µLar, Immunology, Cancer, Neuroscience