Volume : 50 µg
Clone Number :
Aliases : 6330408H09Rik antibody; AI661354 antibody; AV102684 antibody; AW538719 antibody; CAK antibody; CAK complex subunit antibody; ccnh antibody; CCNH_HUMAN antibody; CDK activating kinase antibody; CDK activating kinase complex subunit antibody; Cyclin dependent kinase activating kinase antibody; cyclin dependent kinase activating kinase complex subunit antibody; Cyclin H antibody; Cyclin-H antibody; CyclinH antibody; MO15 associated protein antibody; MO15-associated protein antibody; p34 antibody; p36 antibody; p37 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51946
Immunogen : Recombinant Human Cyclin-H protein (261-319AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1 CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant thro µghout the cell cycle.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CCNH
Research Areas : Epigenetics and Nuclear Signaling; Cell biology