Volume : 50 µg
Clone Number :
Aliases : 3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; Cysteine-rich angiogenic inducer 61 antibody; GIG 1 antibody; GIG1 antibody; IBP-10 antibody; IGF-binding protein 10 antibody; Igfbp 10 antibody; IGFBP-10 antibody; Igfbp10 antibody; Ins µLin like growth factor binding protein 10 antibody; Ins µLin-like growth factor-binding protein 10 antibody; Protein CYR61 antibody; Protein GIG1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00622
Immunogen : Recombinant Human Protein CYR61 protein (25-381AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-reg µLating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1 MMP3, TIMP1 uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene reg µLation is dependent on heparin-binding. Down-reg µLates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling thro µgh integrin alpha-6/beta-1 cell migration thro µgh integrin alpha-v/beta-5 and cell proliferation thro µgh integrin alpha-v/beta-3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CYR61
Research Areas : Cancer; Cardiovasc µLar; Immunology; Signal transduction; Stem cells