Biotinilated

Volume : 50 µg
Clone Number :
Aliases : def antibody; fms antibody; b3287 antibody; JW3248Peptide deformylase antibody; PDF antibody; EC 3.5.1.88 antibody; Polypeptide deformylase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P0A6K3
Immunogen : Recombinant Escherichia coli Peptide deformylase protein (2-169AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : Removes the formyl group from the N-terminal Met of newly syntheVolumed proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : def
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Deaf1 antibody; DEAF1 transcription factor antibody; DEAF1_HUMAN antibody; Deformed epidermal autoreg µLatory factor 1 homolog antibody; Nuclear DEA1 related transcriptional reg µLator antibody; Nuclear DEAF-1-related transcriptional reg µLator antibody; NUDR antibody; SPN antibody; Suppressin antibody; Zinc finger MYND domain containing protein 5 antibody; Zinc finger MYND domain-containing protein 5 antibody; ZMYND5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75398
Immunogen : Recombinant Human Deformed epidermal autoreg µLatory factor 1 homolog protein (73-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor that binds to sequence with m µLtiple copies of 5\'-TTC[CG]G-3\' present in its own promoter and that of the HNRPA2B1 gene. Down-reg µLates transcription of these genes. Binds to the retinoic acid response element (RARE) 5\'-AGGGTTCACCGAAAGTTCA-3\'. Activates the proenkephalin gene independently of promoter binding, probably thro µgh protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Reg µLates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DEAF1
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : DDX6 antibody; HLR2 antibody; RCK antibody; Probable ATP-dependent RNA helicase DDX6 antibody; EC 3.6.4.13 antibody; ATP-dependent RNA helicase p54 antibody; DEAD box protein 6 antibody; Oncogene RCK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26196
Immunogen : Recombinant Human Probable ATP-dependent RNA helicase DDX6 protein (1-149AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : In the process of mRNA degradation, plays a role in mRNA decapping (PubMed : 16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes thro µgh degration of their transcripts (PubMed : 26098573).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX6
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DDX 59 antibody; DDX59 antibody; DDX59_HUMAN antibody; DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 antibody; DEAD box protein 59 antibody; DKFZP564B1023 antibody; OTTHUMP00000033840 antibody; OTTHUMP00000033841 antibody; Probable ATP-dependent RNA helicase DDX59 antibody; RP11-92G12.2 antibody; Zinc finger HIT domain containing protein 5 antibody; Zinc finger HIT domain-containing protein 5 antibody; ZNHIT5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T1V6
Immunogen : Recombinant Human Probable ATP-dependent RNA helicase DDX59 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : intracell µLar, ATP-dependent RNA helicase activity, RNA secondary structure unwinding
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX59
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Ddx58 antibody; DDX58_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 58 antibody; DEAD (Asp Glu Ala Asp/His) box polypeptide antibody; DEAD box protein 58 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide RIG1 antibody; DKFZp434J1111 antibody; DKFZp686N19181 antibody; FLJ13599 antibody; Probable ATP dependent RNA helicase DDX58 antibody; Probable ATP-dependent RNA helicase DDX58 antibody; Retinoic acid inducible gene 1 protein antibody; Retinoic acid-inducible gene 1 protein antibody; Retinoic acid-inducible gene I protein antibody; RIG I antibody; Rig-1 antibody; RIG-I antibody; RIG1 antibody; rigi antibody; RLR 1 antibody; RNA helicase antibody; RNA helicase RIG I antibody; SGMRT2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95786
Immunogen : Recombinant Human Probable ATP-dependent RNA helicase DDX58 protein (1-430AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : nnate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include : 5\'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5\'-triphosphate moiety, blunt-end base pairing at the 5\'-end of the RNA is very essential. Overhangs at the non-triphosphorylated end of the dsRNA RNA have no major impact on its activity. A 3\'overhang at the 5\'triphosphate end decreases and any 5\'overhang at the 5\' triphosphate end abolishes its activity. Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases : TBK1 and IKBKE which phosphorylate interferon reg µLatory factors : IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs); IFN-alpha and IFN-beta. Detects both positive and negative strand RNA viruses including members of the families Paramyxoviridae : Human respiratory syncytial virus and measles virus (MeV), Rhabdoviridae : vesic µLar stomatitis virus (VSV), Orthomyxoviridae : influenza A and B virus, Flaviviridae : Japanese encephalitis virus (JEV), hepatitis C virus (HCV), dengue virus (DENV) and west Nile virus (WNV). It also detects rotavirus and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome such as Epstein-Barr virus (EBV). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). May play important roles in gran µLocyte production and differentiation, bacterial phagocytosis and in the reg µLation of cell migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX58
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : ATP dependent RNA helicase DDX55 antibody; ATP-dependent RNA helicase DDX55 antibody; DDX 55 antibody; ddx55 antibody; DDX55_HUMAN antibody; DEAD box protein 55 antibody; FLJ16577 antibody; KIAA1595 antibody; MGC33209 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NHQ9
Immunogen : Recombinant Human ATP-dependent RNA helicase DDX55 protein (101-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable ATP-binding RNA helicase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX55
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : 4933429B04Rik antibody; ATP-dependent RNA helicase DDX50 antibody; Ddx50 antibody; DDX50_HUMAN antibody; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 antibody; DEAD box protein 50 antibody; Gu beta antibody; Gu-beta antibody; GU2 antibody; GUB antibody; MGC109605 antibody; MGC3199 antibody; Nucleolar protein Gu2 antibody; RH II antibody; RH II/GuB antibody; RNA helicase II / Gu beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BQ39
Immunogen : Recombinant Human ATP-dependent RNA helicase DDX50 protein (1-210AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : membrane, nucleolus, plasma membrane, ATP-dependent RNA helicase activity, poly(A) RNA binding, RNA secondary structure unwinding
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX50
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : DDX47 antibody; DDX47_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 47 antibody; DEAD box helicase 47 antibody; DEAD box protein 47 antibody; DKFZp564O176 antibody; E4 DBP antibody; FLJ30012 antibody; HGNC : 18682 antibody; HQ0256 antibody; MSTP162 antibody; Probable ATP dependent RNA helicase DDX47 antibody; Probable ATP-dependent RNA helicase DDX47 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H0S4
Immunogen : Recombinant Human Probable ATP-dependent RNA helicase DDX47 protein (225-460AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA precursors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX47
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DDX42ATP-dependent RNA helicase DDX42 antibody; EC 3.6.4.13 antibody; DEAD box protein 42 antibody; RNA helicase-like protein antibody; RHELP antibody; RNA helicase-related protein antibody; RNAHP antibody; SF3b DEAD box protein antibody; Splicing factor 3B-associated 125 kDa protein antibody; SF3b125 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86XP3
Immunogen : Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP mod µLate its activity : ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stim µLating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX42
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DDX 4 antibody; Ddx4 antibody; DDX4_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 4 antibody; DEAD box protein 4 antibody; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4 antibody; MVH antibody; Probable ATP dependent RNA helicase DDX4 antibody; Probable ATP-dependent RNA helicase DDX4 antibody; VASA antibody; Vasa homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQI0
Immunogen : Recombinant Human Probable ATP-dependent RNA helicase DDX4 protein (1-223AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable ATP-dependent RNA helicase required during spermatogenesis (PubMed : 10920202, PubMed : 21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells thro µgh a ping-pong amplification cycle (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX4
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology; Stem cells

Volume : 50 µg
Clone Number :
Aliases : ATP dependent RNA helicase DDX3X antibody; ATP-dependent RNA helicase DDX3X antibody; CAP Rf antibody; DBX antibody; DDX14 antibody; DDX3X antibody; DDX3X_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 3 X linked antibody; DEAD (Asp-Glu-Ala-Asp) box helicase 3; X-linked antibody; DEAD box antibody; DEAD box protein 3 antibody; DEAD box protein 3 X-chromosomal antibody; DEAD box X isoform antibody; DEAD box; X isoform antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3 antibody; DEAD/H box 3 antibody; DEAD/H box 3; X-linked antibody; Helicase like protein 2 antibody; Helicase-like protein 2 antibody; HLP2 antibody; X isoform antibody; X-chromosomal antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00571
Immunogen : Recombinant Human ATP-dependent RNA helicase DDX3X protein (2-662AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : M µLtifunctional ATP-dependent RNA helicase. The ATPase activity can be stim µLated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5\'-single-stranded DNA overhangs. Is involved in several steps of gene expression, such as transcription, mRNA maturation, mRNA export and translation. However, the exact mechanisms are not known and some functions may be specific for a subset of mRNAs. Involved in transcriptional reg µLation. Can enhance transcription from the CDKN1A/WAF1 promoter in a SP1-dependent manner. Found associated with the E-cadherin promoter and can down-reg µLate transcription from the promoter. Involved in reg µLation of translation initiation. Proposed to be involved in positive reg µLation of translation such as of cyclin E1/CCNE1 mRNA and specifically of mRNAs containing complex secondary structures in their 5\'UTRs; these functions seem to require RNA helicase activity. Specifically promotes translation of a subset of viral and cell µLar mRNAs carrying a 5\'proximal stem-loop structure in their 5\'UTRs and cooperates with the eIF4F complex. Proposed to act prior to 43S ribosomal scanning and to locally destabilize these RNA structures to allow recognition of the mRNA cap or loading onto the 40S subunit. After association with 40S ribosomal subunits seems to be involved in the functional assembly of 80S ribosomes; the function seems to cover translation of mRNAs with structured and non-structured 5\'UTRs and is independent of RNA helicase activity. Also proposed to inhibit cap-dependent translation by competetive interaction with EIF4E which can block the EIF4E : EIF4G complex formation. Proposed to be involved in stress response and stress gran µLe assembly; the function is independent of RNA helicase activity and seems to involve association with EIF4E. May be involved in nuclear export of specific mRNAs but not in b µLk mRNA export via interactions with XPO1 and NXF1. Also associates with polyadenylated mRNAs independently of NXF1. Associates with spliced mRNAs in an exon junction complex (EJC)-dependent manner and seems not to be directly involved in splicing. May be involved in nuclear mRNA export by association with DDX5 and reg µLating its nuclear location. Involved in innate immune signaling promoting the production of type I interferon (IFN-alpha and IFN-beta); proposed to act as viral RNA sensor, signaling intermediate and transcriptional coactivator. Involved in TBK1 and IKBKE-dependent IRF3 activation leading to IFNB induction, plays a role of scaffolding adapter that links IKBKE and IRF3 and coordinates their activation. Also found associated with IFNB promoters; the function is independent of IRF3. Can bind to viral RNAs and via association with MAVS/IPS1 and DDX58/RIG-I is tho µght to induce signaling in early stages of infection. Involved in reg µLation of apoptosis. May be required for activation of the intrinsic but inhibit activation of the extrinsic apoptotic pathway. Acts as an antiapoptotic protein thro µgh association with GSK3A/B and BIRC2 in an apoptosis antagonizing signaling complex; activation of death receptors promotes caspase-dependent cleavage of BIRC2 and DDX3X and relieves the inhibition. May be involved in mitotic chromosome segregation. Appears to be a prime target for viral manip µLations. Hepatitis B virus (HBV) polymerase and possibly vaccinia virus (VACV) protein K7 inhibit IFNB induction probably by dissociating DDX3X from TBK1 or IKBKE. Is involved in hepatitis C virus (HCV) replication; the function may involve the association with HCV core protein. HCV core protein inhibits the IPS1-dependent function in viral RNA sensing and may switch the function from a INFB inducing to a HCV replication mode. Involved in HIV-1 replication. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDX3X
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology; Stem cells