Volume : 50 µg
Clone Number :
Aliases : Efnb3Ephrin-B3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : O35393
Immunogen : Recombinant Mouse Ephrin-B3 protein (28-227AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, rep µLsion and adhesion during neuronal, vasc µLar and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Efnb3
Research Areas : Neuroscience; Cardiovasc µLar